Description

Liensinine is a bioactive bisbenzylisoquinoline alkaloid, a key reference standard for pharmaceutical research and development. Its significance lies in its role as a primary analytical marker for quality control and pharmacological studies of Nelumbo nucifera (lotus) extracts. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and natural product chemistry sectors who require reliable, well-characterized materials for method validation and bioactivity screening.

Application

• Pharmaceutical Reference Standard: Primary use as a certified reference material (CRM) for the identification and quantification of liensinine in raw materials and finished products.
• Bioactivity Research: Used in in-vitro and in-vivo studies to investigate its pharmacological properties, including potential anti-cancer, anti-arrhythmic, and anti-hypertensive effects.
• Analytical Method Development: Critical for developing and validating HPLC, LC-MS, and other chromatographic methods for quality control of lotus seed embryo or related botanical extracts.
• Nutraceutical Standardization: Serves as a marker compound to standardize and assure the potency and consistency of dietary supplements derived from Nelumbo nucifera.
• Chemical Synthesis & Derivatization: Acts as a starting material or intermediate for the semi-synthesis of novel derivatives to explore structure-activity relationships (SAR).
• Academic & Institutional Research: Supplied to universities and research institutes for fundamental studies on isoquinoline alkaloids and their mechanisms of action.

Basic Information

Product Name	Liensinine
CAS No.	2586-96-1
Molecular Formula	C37H42N2O6
Molecular Weight	610.74 g/mol
Synonyms	Liensinine; (1R)-1-[(4-Hydroxyphenyl)methyl]-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-2-ium; 1-[(4-Hydroxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinoline; Liensinine alkaloid; Lotusine B (related); Bisbenzylisoquinoline Alkaloid
EINECS	Contact for details

Quality Control

Our Liensinine is produced under a strict quality management system. Each batch is characterized and tested using advanced analytical techniques including HPLC, MS, and NMR to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with detailed chromatographic data upon request, supporting compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C under inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.