Description

Butyrylcholine Iodide is a quaternary ammonium salt and a synthetic choline ester, widely recognized as a specific substrate for the enzyme butyrylcholinesterase (BuChE). This compound is essential for biochemical research and diagnostic applications, enabling the study of cholinesterase activity and inhibition. It is a critical reagent for researchers and manufacturers in the pharmaceutical, life sciences, and clinical diagnostics sectors, particularly for developing assays related to neurodegenerative diseases and toxicology.

Application

• Enzyme Substrate for Butyrylcholinesterase (BuChE): Primary use as a specific chromogenic or fluorogenic substrate in enzymatic assays to measure BuChE activity.
• Biochemical Research: Fundamental tool for studying cholinesterase kinetics, enzyme inhibition mechanisms, and structure-activity relationships in academic and industrial R&D.
• Pharmaceutical Screening: Used in high-throughput screening (HTS) platforms to identify and evaluate potential inhibitors for Alzheimer's disease and other neurological disorders.
• Clinical Diagnostics: Key component in diagnostic kits for measuring serum cholinesterase levels, which can indicate exposure to organophosphate or carbamate pesticides.
• Neuroscience Studies: Employed in research models to understand the role of butyrylcholinesterase in the central nervous system and its interplay with acetylcholine signaling.
• Toxicology & Environmental Monitoring: Applied in assays designed to detect and quantify anticholinesterase agents in environmental or biological samples.

Basic Information

Product Name	Butyrylcholine Iodide
CAS No.	2494-56-6
Molecular Formula	C9H20INO2
Molecular Weight	285.17 g/mol
Synonyms	Butyrylcholine iodide; (2-Butanoyloxyethyl)trimethylammonium iodide; Butanoylcholine iodide; Butyroylcholine iodide; N,N,N-Trimethyl-2-(1-oxobutoxy)ethanaminium iodide; BChI; Butyrylthiocholine iodide precursor
EINECS	219-691-7

Quality Control

Our Butyrylcholine Iodide is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Melting Point	Approx. 160-165°C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.