Description

1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate is a specialized carbodiimide reagent primarily used as a zero-length coupling agent for the formation of amide bonds. This compound matters for its efficiency in mediating peptide synthesis and bioconjugation reactions under mild conditions, offering a reliable alternative to other coupling agents. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and peptide synthesis industries who require high-purity, effective reagents for constructing complex molecular architectures.

Application

• Peptide Synthesis: A key coupling agent for solid-phase and solution-phase peptide synthesis, facilitating the formation of amide bonds between amino acids.
• Bioconjugation: Used to crosslink biomolecules, such as proteins and antibodies, to other molecules, polymers, or surfaces for diagnostic and therapeutic applications.
• Polymer Chemistry: Employed in the synthesis of polyamides, polyurethanes, and other step-growth polymers requiring carbodiimide-mediated condensation reactions.
• Organic Synthesis: Acts as a dehydrating agent for the preparation of esters, anhydrides, and other carboxylic acid derivatives from corresponding acids.
• Pharmaceutical Intermediates: Serves as a critical reagent in the multistep synthesis of active pharmaceutical ingredients (APIs) and complex organic molecules.
• Biomaterial Fabrication: Utilized in the modification and functionalization of hydrogels and other biomaterials to introduce specific bioactive ligands.

Basic Information

Product Name	1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate
CAS No.	2491-17-0
Molecular Formula	C21H33N3O4S
Molecular Weight	423.57 g/mol
Synonyms	CMC; CMC Hydrochloride (common misnomer); 1-Cyclohexyl-3-(2-morpholinoethyl)carbodiimide Methyl-p-toluenesulfonate; CMEC; Morpho CDI; (Cyclohexyl)[2-(4-morpholinyl)ethyl]carbodiimide Methyl-p-toluenesulfonate; 1-Cyclohexyl-3-(2-morpholin-4-ylethyl)carbodiimide 4-Methylbenzenesulfonate; Carbodiimide, 1-cyclohexyl-3-[2-(4-morpholinyl)ethyl]-, methyl-p-toluenesulfonate
EINECS	Contact for details

Quality Control

Our 1-Cyclohexyl-3-(2-Morpholinoethyl)Carbodiimide Metho-p-Toluenesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and production applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and efficacy.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.