Description

N,1-O,3-o-Triacetylsphingosine is a key acetylated derivative of sphingosine, a fundamental building block of sphingolipids. This compound is essential for biochemical research and pharmaceutical development, serving as a crucial intermediate and reference standard. It is primarily utilized by researchers and manufacturers in the life sciences, pharmaceutical, and biotechnology sectors for studying cell signaling, lipid metabolism, and developing novel therapeutics.

Application

• Biochemical Research: A vital intermediate in the synthesis and study of complex sphingolipids and their metabolic pathways.
• Pharmaceutical Development: Used as a reference standard and building block in the research and development of drugs targeting lipid-related disorders and cancer.
• Cell Biology Studies: Employed to investigate the role of sphingolipids in cell signaling, apoptosis (programmed cell death), and membrane structure.
• Enzyme Substrate: Acts as a substrate for enzymes like ceramidases and sphingosine kinases in enzymatic assays and inhibitor screening.
• Metabolite Analysis: Serves as a standard for the qualitative and quantitative analysis of sphingolipid metabolites in biological samples via LC-MS or HPLC.
• Academic Research: A critical reagent for universities and research institutes exploring lipidomics and the biochemical basis of disease.

Basic Information

Product Name	N,1-O,3-o-Triacetylsphingosine
CAS No.	2482-37-3
Molecular Formula	C24H45NO5
Molecular Weight	427.62 g/mol
Synonyms	N-Acetylsphingosine Triacetate; D-erythro-Sphingosine, N,1,3-triacetate; Sphingosine N,1,3-Triacetate; 2S,3R,4E-2-Acetamido-1,3-diacetoxy-4-octadecene; Ceramide Triacetate; N-Acetyl-D-erythro-sphingosine 1,3-Diacetate; (2S,3R,4E)-2-(Acetylamino)-1,3-diacetoxy-4-octadecene
EINECS	219-632-9

Quality Control

Our N,1-O,3-o-Triacetylsphingosine is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.