Description

1,3,5(10)-Estratrien-3-Ol-17-One 3(o->1Beta)-D-Glycopyranosiduronic Acid is a specific estrogen conjugate, a chemically defined metabolite of estradiol. This compound is of significant value as a high-purity reference standard and a critical intermediate in pharmaceutical research and development. It is primarily needed by manufacturers and research institutions in the pharmaceutical, biotechnology, and diagnostic sectors for analytical method development, metabolic studies, and the synthesis of more complex steroid derivatives.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments (HPLC, LC-MS) to ensure accurate quantification of estrogen metabolites in research and quality control.
• Biochemical Research: Serves as a key reagent in studies of estrogen metabolism, hormone conjugation pathways, and steroid biochemistry.
• Diagnostic Kit Development: Employed as a critical component in the development and validation of immunoassays and other diagnostic tests for hormonal analysis.
• Advanced Intermediate: Acts as a sophisticated building block for the chemical synthesis of novel steroid-based therapeutic agents or labeled compounds.
• Metabolite Identification: Used as an authentic standard to identify and confirm the presence of this specific conjugate in in-vitro or in-vivo metabolism studies.

Basic Information

Product Name	1,3,5(10)-Estratrien-3-Ol-17-One 3(o->1Beta)-D-Glycopyranosiduronic Acid
CAS No.	2479-90-5
Molecular Formula	C24H32O8
Molecular Weight	448.51 g/mol
Synonyms	Estradiol 3-Glucuronide; 17β-Estradiol 3-β-D-Glucuronide; E2-3G; Estradiol 3-β-D-Glucopyranosiduronic Acid; 3-Hydroxyestra-1,3,5(10)-trien-17-one 3-Glucuronide; Estrone 3-Glucuronide (common misnomer, often used interchangeably); 3-Glucuronosyl estradiol; NSC 113492
EINECS	Contact for details

Quality Control

Our 1,3,5(10)-Estratrien-3-Ol-17-One 3(o->1Beta)-D-Glycopyranosiduronic Acid is produced and handled under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.