Description

4-Des-Dimethylaminotetracycline is a key intermediate and derivative in the tetracycline class of antibiotics. This compound is of significant interest for pharmaceutical research and development, particularly in the study of antibiotic structure-activity relationships and the synthesis of novel therapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in antibiotic development and production.

Application

• Pharmaceutical Intermediate: A critical building block in the research and synthesis of novel tetracycline-based antibiotics and derivatives.
• Biochemical Research: Used as a reference standard and tool compound in studies investigating the mechanism of action and resistance of tetracycline antibiotics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a precursor in the development and scale-up processes for new antibiotic APIs.
• Microbiology Studies: Employed in laboratory research to understand bacterial protein synthesis inhibition and to develop new antimicrobial agents.
• Veterinary Medicine Research: Investigated for potential applications in developing new treatments for animal health.

Basic Information

Product Name	4-Des-Dimethylaminotetracycline
CAS No.	2444-65-7
Molecular Formula	C₂₁H₂₂N₂O₈
Molecular Weight	430.41 g/mol
Synonyms	4-Dedimethylaminotetracycline; 4-Desdimethylaminotetracycline; 4-DDATC; 4-DDMAT; NSC 107428; Tetracycline, 4-des(dimethylamino)-; 2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-
EINECS	Contact for details

Quality Control

Our 4-Des-Dimethylaminotetracycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and pharmaceutical applications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.