Description

1,2-Dioleoyl-Rac-Glycerol is a high-purity synthetic glyceride, specifically a diacylglycerol (DAG) where the 1- and 2- positions are esterified with oleic acid. This compound serves as a critical intermediate and functional excipient in advanced pharmaceutical and nutraceutical formulations, valued for its role in lipid-based drug delivery systems. It is essential for researchers and manufacturers in the pharmaceutical, cosmetic, and specialty chemical industries who require precise lipid components for enhancing bioavailability, creating emulsions, or studying lipid metabolism.

Application

• Pharmaceutical Excipient: Key component in lipid-based drug delivery systems (e.g., self-emulsifying drug delivery systems - SEDDS) to improve the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a substrate or standard in enzymatic studies of lipases, phospholipases, and lipid metabolism pathways.
• Cosmetic Formulations: Acts as an emollient and skin-conditioning agent in high-end skincare products, contributing to texture and stability.
• Nutraceutical Intermediate: Serves as a precursor in the synthesis of structured lipids and other bioactive compounds for dietary supplements.
• Liposome & Nanoparticle Preparation: Utilized as a lipid component in the fabrication of liposomes and solid lipid nanoparticles (SLNs) for targeted delivery applications.
• Reference Standard: Employed as an analytical standard in chromatography (HPLC, GC) for quality control and method development in lipid analysis.

Basic Information

Product Name	1,2-Dioleoyl-Rac-Glycerol
CAS No.	2442-61-7
Molecular Formula	C39H72O5
Molecular Weight	621.00 g/mol
Synonyms	1,2-Dioleoyl-rac-glycerol; rac-1,2-Dioleoylglycerol; Diolein (mixed isomer); 1,2-Di-(cis-9-octadecenoyl)-rac-glycerol; Glycerol 1,2-dioleate; DG(18:1/18:1/0:0); 1,2-Di-O-oleoyl-rac-glycerol; 9-Octadecenoic acid (9Z)-, 1,1'-(1-[(1-hydroxy-2-oxo-1,2-ethanediyl)oxy]methyl)-1,2-ethanediyl ester
EINECS	219-473-6

Quality Control

Our 1,2-Dioleoyl-Rac-Glycerol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical and research applications. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen) at 2-8°C to minimize oxidation and maintain stability. Keep the container in a cool, dry, and well-ventilated area away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
1,3-Dioleoyl Isomer (HPLC)	≤ 3.0%
Monoolein (HPLC)	≤ 2.0%
Acid Value	≤ 2.0 mg KOH/g
Peroxide Value	≤ 5.0 meq/kg
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.