Description

(5Beta,17Beta)-17-Methyl-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol CAS NO 2435-90-7 is a high-purity, specialized steroid derivative featuring a photoactivatable diazirine group. This compound is critical for advanced biochemical research, particularly in photoaffinity labeling studies to map protein-ligand interactions and receptor binding sites with high precision. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on drug discovery and structural biology.

Application

• Photoaffinity Labeling Probes: Acts as a key intermediate or active probe in the synthesis of photoactivatable ligands for studying steroid hormone receptors and other protein targets.
• Drug Discovery Research: Used in target identification and validation studies to elucidate the binding mechanisms of novel therapeutic compounds.
• Biochemical Tool Development: Incorporated into cross-linking reagents and molecular probes for proteomics and interactome analysis.
• Metabolic Pathway Studies: Employed to trace and analyze steroid metabolism and biosynthesis pathways in biological systems.
• Reference Standard: Serves as an analytical standard in method development and quality control for related pharmaceutical compounds.

Basic Information

Item	Detail
Product Name	(5Beta,17Beta)-17-Methyl-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol
CAS No.	2435-90-7
Molecular Formula	C₂₁H₃₂N₂O
Molecular Weight	328.50 g/mol
Synonyms	17β-Hydroxy-17α-methyl-5β-androstan-3α-yl diazirine; 17-Methylandrostan-17-ol-3-spiro-3'-diazirine; 3-(3H-Diazirin-3-yl)-17β-hydroxy-17α-methylandrostane; Diazirine Androstane Derivative; Photoactivatable Androstane; [³H]Diazirine Androstanol; Research Compound 2435-90-7
EINECS	Contact for details

Quality Control

Every batch of (5Beta,17Beta)-17-Methyl-Spiro[Androstane-3,3'-[3H]Diazirin]-17-Ol is produced and analyzed under strict quality management protocols. We guarantee high chemical purity and isotopic enrichment as required for sensitive research applications. Comprehensive analytical testing, including HPLC, NMR, and MS, is performed to verify identity, purity, and stability. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is strictly light-sensitive and must be handled under subdued light or in amber glass to prevent decomposition. Allow the container to reach room temperature in a dark environment before opening to avoid moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Specific Activity	Customizable (Contact for details)
Radiochemical Purity	≥ 97%
Solubility	Soluble in common organic solvents (e.g., DMSO, Ethanol)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.