Description

Neferine is a prominent bisbenzylisoquinoline alkaloid isolated from the seed embryo of *Nelumbo nucifera* (lotus). This compound is of significant interest due to its diverse and potent pharmacological profile, offering a high-purity standard for research and development. It is primarily sought after by the pharmaceutical, nutraceutical, and advanced life science industries for its bioactive potential. Our supply ensures consistent quality and reliable availability for critical applications worldwide.

Application

• Pharmaceutical R&D: Core ingredient for investigating anti-hypertensive, anti-arrhythmic, and anti-thrombotic therapies.
• Cardiovascular Research: Used in studies targeting calcium channel blockade, vasodilation, and protection against myocardial ischemia.
• Metabolic Disorder Studies: Key compound for research into anti-diabetic and anti-obesity mechanisms, including insulin sensitivity and lipid metabolism.
• Neuropharmacology: Employed in preclinical research for its neuroprotective, anti-depressant, and anti-anxiety effects.
• Anti-inflammatory & Immunomodulation: Investigated for its ability to modulate inflammatory pathways and cytokine production.
• Anti-fibrosis Research: Studied for its potential to inhibit tissue fibrosis in liver, lung, and cardiac models.
• Natural Product Standard: Serves as a high-purity reference standard for quality control in herbal extract manufacturing and analytical testing.
• Nutraceutical Formulation: Used in the development of advanced dietary supplements targeting metabolic and cardiovascular health.

Basic Information

Product Name	Neferine
CAS No.	2292-16-2
Molecular Formula	C38H44N2O6
Molecular Weight	624.77 g/mol
Synonyms	Liensinine isomer; (1R)-1-[[(1R)-6,7-Dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-2-[[(1S)-6,7-dimethoxy-2-methyl-3,4-dihydro-1H-isoquinolin-1-yl]methyl]-6,7-dimethoxy-1,2,3,4-tetrahydroisoquinoline; Neferin; Lotusine B
EINECS	Contact for details

Quality Control

Our Neferine is produced under strict quality management systems to ensure it meets the exacting standards required for research and development. Each batch is subjected to comprehensive analytical testing, including HPLC for purity verification and structural confirmation via MS and NMR. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.2%
Heavy Metals	≤20 ppm
Solvent Residues	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.