Description

Guanylyl(3'-5')Uridine 3'-Monophosphate is a key nucleotide derivative and a fundamental building block in biochemical research and synthesis. This compound is essential for studying RNA structure, function, and enzymatic processes, offering high purity and reliability for critical applications. It is primarily utilized by research institutions, pharmaceutical developers, and biotechnology companies engaged in oligonucleotide synthesis, molecular biology, and diagnostic assay development.

Application

• Oligonucleotide Synthesis: Serves as a crucial phosphoramidite or solid-phase synthesis intermediate for constructing specific RNA sequences.
• Biochemical Research: Used as a substrate or standard in enzymatic studies, particularly those involving RNA polymerases, ligases, and nucleases.
• Pharmaceutical Development: Acts as a raw material in the research and development of nucleotide-based therapeutics, including antisense oligonucleotides and aptamers.
• Diagnostic Reagents: Employed in the formulation of probes and primers for molecular diagnostics, PCR, and next-generation sequencing applications.
• Enzyme Mechanism Studies: Utilized to investigate the kinetics and specificity of enzymes that recognize or modify guanosine-uridine dinucleotide motifs.
• Reference Standard: Provides a high-purity analytical standard for quality control and method validation in analytical laboratories.

Basic Information

Item	Details
Product Name	Guanylyl(3'-5')Uridine 3'-Monophosphate
CAS No.	2240-05-3
Molecular Formula	C19H25N7O16P2
Molecular Weight	669.39 g/mol
Synonyms	GpU; Guanosine(3'-5')uridine monophosphate; 5'-GMP-3'-UMP; 3'-UMP-5'-GMP; Guanylyl-uridine monophosphate; G(3'-5')U; GpU 3'-monophosphate; Uridine, guanylyl-(3'->5')-, 3'-(dihydrogen phosphate)
EINECS	Contact for details

Quality Control

Our Guanylyl(3'-5')Uridine 3'-Monophosphate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced analytical techniques such as HPLC and NMR. We adhere to relevant industry guidelines to support our customers' quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept sealed in a dry environment to prevent moisture absorption, which can affect stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Related Substances (HPLC)	Total impurities ≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.