Description

[3-Hydroxy-2,2-Dimethyl-3-[2-(2-Sulfanylethylcarbamoyl)Ethylcarbamoyl]Propoxy]Phosphonic Acid is a specialized organophosphorus compound featuring a unique molecular structure that combines phosphonic acid, carbamoyl, and sulfanyl (thiol) functional groups. This multi-functional nature makes it a valuable intermediate for synthesizing complex molecules and modifying material surfaces. It is primarily sought after by research and development teams in the pharmaceutical and specialty chemical sectors. Its specific reactivity profile enables applications in drug discovery, polymer science, and the development of novel chelating agents or surface modifiers.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzyme inhibition or metal chelation.
• Bioconjugation Reagent: Utilized for coupling biomolecules (e.g., peptides, proteins) to surfaces or other molecules via its reactive thiol and carbamoyl groups.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce phosphonic acid and thiol groups into polymers, enhancing properties like adhesion, flame retardancy, or metal-binding capacity.
• Metal Chelation & Sequestration: The phosphonic acid moiety provides strong binding affinity for di- and trivalent metal ions, useful in water treatment, scale inhibition, and analytical chemistry.
• Surface Functionalization: Used to create self-assembled monolayers (SAMs) on metal or oxide surfaces, imparting specific chemical functionality for sensors, catalysis, or corrosion protection.
• Research Chemical: Employed in academic and industrial R&D for exploring new reaction pathways and creating libraries of compounds for high-throughput screening.

Basic Information

Product Name	[3-Hydroxy-2,2-Dimethyl-3-[2-(2-Sulfanylethylcarbamoyl)Ethylcarbamoyl]Propoxy]Phosphonic Acid
CAS No.	2226-71-3
Molecular Formula	C11H21N2O7PS
Molecular Weight	356.33 g/mol
Synonyms	3-Hydroxy-2,2-dimethyl-3-({2-[(2-sulfanylethyl)carbamoyl]ethyl}carbamoyl)propoxyphosphonic acid; Phosphonic acid, P-[3-[[2-[[(2-mercaptoethyl)amino]carbonyl]ethyl]amino]-2,2-dimethyl-3-oxopropyl]-; N-[2-[[(2-Mercaptoethyl)amino]carbonyl]ethyl]-3-hydroxy-2,2-dimethyl-3-(phosphonooxy)propanamide; Thiol-functionalized phosphonic acid derivative; Carbamoyl ethyl sulfanyl phosphonate; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of [3-Hydroxy-2,2-Dimethyl-3-[2-(2-Sulfanylethylcarbamoyl)Ethylcarbamoyl]Propoxy]Phosphonic Acid is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. For custom synthesis projects, we adhere to cGMP guidelines as required.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. This material is both light-sensitive and easily oxidized. Keep the container tightly sealed in a dry, cool, and well-ventilated place. Separate from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.