Description

3-[[2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl](3-Methylphenyl)Amino]Propiononitrile is a specialized chemical intermediate featuring a maleimide-reactive group and a cyanoethyl moiety, making it a valuable building block for advanced synthesis. This compound matters for its role in creating functionalized polymers, cross-linking agents, and bioconjugation reagents where controlled reactivity and specific linkage are required. Industries such as pharmaceuticals, advanced materials science, and specialty polymer manufacturing need this high-purity intermediate for research and production.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs).
• Polymer Cross-Linking Agent: Used to introduce reactive maleimide sites into polymer backbones for creating hydrogels and smart materials.
• Bioconjugation Reagent: Facilitates the site-specific labeling and modification of proteins, peptides, and other biomolecules.
• Surface Functionalization: Employed to modify material surfaces (e.g., nanoparticles, chips) with reactive groups for further chemical attachment.
• Research & Development: A critical tool in organic and medicinal chemistry for exploring new synthetic pathways and molecular architectures.
• Specialty Adhesives & Coatings: Imparts specific curing and adhesion properties in high-performance industrial formulations.

Basic Information

Product Name	3-[[2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl](3-Methylphenyl)Amino]Propiononitrile
CAS No.	2223-89-4
Molecular Formula	C₁₇H₂₀N₄O₂
Molecular Weight	312.37 g/mol
Synonyms	N-(2-Cyanoethyl)-N-(2-(2,5-dioxo-1-pyrrolidinyl)ethyl)-m-toluidine; 1-[2-[[3-Methylphenyl)(2-cyanoethyl)amino]ethyl]-2,5-pyrrolidinedione; N-(2-Cyanoethyl)-N-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]-3-methylaniline; m-Toluidine, N-(2-cyanoethyl)-N-[2-(2,5-dioxo-1-pyrrolidinyl)ethyl]-; 3-[[2-(2,5-Dioxo-1-pyrrolidinyl)ethyl](3-methylphenyl)amino]propiononitrile; Maleimide-PEG2-C2-cyanoethyl linker; Contact for additional trade names.
EINECS	Contact for details

Quality Control

Our 3-[[2-(2,5-Dioxopyrrolidin-1-Yl)Ethyl](3-Methylphenyl)Amino]Propiononitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.