Description

Coclaurine is a naturally occurring isoquinoline alkaloid of significant interest in advanced organic synthesis and pharmaceutical research. Its unique tetracyclic structure serves as a versatile intermediate for the development of complex bioactive molecules. This compound is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel therapeutic agents and the study of alkaloid chemistry.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of complex alkaloids and potential active pharmaceutical ingredients (APIs).
• Neurological Research: Used in preclinical studies to investigate interactions with neurotransmitter systems due to its structural similarity to other bioactive isoquinolines.
• Organic Synthesis: Serves as a sophisticated starting material or intermediate in multi-step synthetic routes for natural product analogs.
• Biochemical Tool Compound: Employed in vitro to study specific enzymatic pathways or receptor binding activities relevant to medicinal chemistry.
• Reference Standard: Provides a high-purity benchmark for analytical method development and quality control in pharmaceutical laboratories.

Basic Information

Product Name	Coclaurine
CAS No.	2196-60-3
Molecular Formula	C17H19NO3
Molecular Weight	285.34 g/mol
Synonyms	1,2,3,4-Tetrahydro-1-[(4-hydroxyphenyl)methyl]-6,7-isoquinolinediol; (S)-Coclaurine; Norcoclaurine; Higenamine 4'-O-methyl ether; NSC 51046; 6,7-Dihydroxy-1-(4-hydroxybenzyl)-1,2,3,4-tetrahydroisoquinoline
EINECS	218-603-7

Quality Control

Our Coclaurine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We support compliance with relevant guidelines for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.