Description

Vindoline is a monoterpenoid indole alkaloid primarily isolated from the Madagascar periwinkle plant, *Catharanthus roseus*. This compound serves as a crucial intermediate in the semi-synthetic production of complex anti-cancer agents, most notably vinblastine and vincristine. It is therefore an essential building block for pharmaceutical manufacturers and research institutions focused on oncology drug development and natural product chemistry.

Application

• Pharmaceutical Intermediate: Key precursor in the semi-synthesis of the vital chemotherapeutic agents vinblastine and vincristine.
• Biochemical Research: Used as a reference standard and active compound in studies of alkaloid biosynthesis, anti-cancer mechanisms, and cell biology.
• Natural Product Isolation: Serves as a target molecule for extraction and purification process development from plant sources.
• Medicinal Chemistry: Utilized as a core scaffold for the synthesis of novel analogs with potential therapeutic activity.
• Quality Control: Employed as an analytical standard in HPLC and LC-MS methods for the quality assurance of related alkaloids and botanical extracts.

Basic Information

Product Name	Vindoline
CAS No.	2182-14-1
Molecular Formula	C25H32N2O6
Molecular Weight	456.53 g/mol
Synonyms	Vindoline; (3aR,4R,5S,5aR,10bR,13aR)-4-(Acetyloxy)-3a-ethyl-9-((2R,4S,5S)-4-ethyl-5-hydroxy-6-methyloxan-2-yl)-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylic acid methyl ester; Catharanthine, 17-deacetoxy-16-demethoxy-; NSC 56362
EINECS	218-562-2

Quality Control

Our Vindoline is produced and tested under strict quality management protocols. Each batch is analyzed to ensure high purity and identity, with specifications typically meeting or exceeding research-grade standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical research and development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.5 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.