Description

(19S)-19-Acetyloxy-2,16-Didehydro-20-Hydroxycuran-17-Oic Acid Methyl Ester is a high-purity, semi-synthetic alkaloid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate for the synthesis of novel therapeutic agents, particularly in the exploration of central nervous system (CNS) and neuromuscular modulators. It is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on developing new drug candidates and studying complex natural product derivatives.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex alkaloid-based active pharmaceutical ingredients (APIs).
• Neuromuscular Research: Used as a reference standard and precursor in studies targeting nicotinic acetylcholine receptors and related pathways.
• Medicinal Chemistry: Serves as a sophisticated scaffold for structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Analytical Standard: Employed as a high-purity certified reference material (CRM) for method development and quality control in analytical laboratories.
• Natural Product Synthesis: A crucial intermediate in the total or semi-synthesis of complex curan-type alkaloids and their analogs.
• Biochemical Research: Utilized in pharmacological assays to investigate mechanisms of action and receptor binding profiles.

Basic Information

Product Name	(19S)-19-Acetyloxy-2,16-Didehydro-20-Hydroxycuran-17-Oic Acid Methyl Ester
CAS No.	2111-86-6
Molecular Formula	C23H28N2O5
Molecular Weight	412.48 g/mol
Synonyms	19-Acetoxy-2,16-didehydro-20-hydroxycuran-17-oic acid methyl ester; Methyl (19S)-19-acetyloxy-2,16-didehydro-20-hydroxycuran-17-oate; 19-Acetyloxy-2,16-didehydro-20-hydroxycuran-17-oic acid methyl ester; Curan-17-oic acid, 19-(acetyloxy)-2,16-didehydro-20-hydroxy-, methyl ester, (19S)-; 2111-86-6; A derivative of C-curarine I; A semi-synthetic curane alkaloid ester.
EINECS	Contact for details

Quality Control

Our (19S)-19-Acetyloxy-2,16-Didehydro-20-Hydroxycuran-17-Oic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light). For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.