Description

Glucosyl Fluoride is a specialized fluorinated carbohydrate derivative that serves as a crucial biochemical tool and synthetic intermediate. Its primary value lies in its role as a potent and specific inhibitor of glycosidases, enabling critical research in enzymology and carbohydrate chemistry. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors, particularly for studying enzyme mechanisms and developing glycosidase-targeted therapeutics. The product is supplied under the identifier CAS NO 2106-10-7.

Application

• Glycosidase Inhibition Studies: Acts as a mechanism-based inactivator for fundamental research on enzymes like α-glucosidase and β-glucosidase.
• Pharmaceutical Research: Used as a key intermediate in the synthesis of novel glycosidase inhibitors with potential therapeutic applications for diabetes, viral infections, and lysosomal storage disorders.
• Biochemical Probe Development: Serves as a precursor for active-site labeling reagents and fluorescent probes to study carbohydrate-active enzymes.
• Enzyme Mechanism Elucidation: Provides insights into the catalytic mechanisms of retaining glycosidases through transition-state analog studies.
• Diagnostic Reagent Formulation: Employed in the development of enzymatic assay kits for clinical and research diagnostics.
• Carbohydrate Chemistry Synthesis: Utilized as a glycosyl donor in specialized synthetic routes for constructing complex oligosaccharides and glycoconjugates.

Basic Information

Product Name	Glucosyl Fluoride
CAS No.	2106-10-7
Molecular Formula	C6H11FO5
Molecular Weight	182.15 g/mol
Synonyms	α-D-Glucopyranosyl Fluoride; D-Glucosyl Fluoride; 1-Fluoro-α-D-glucopyranose; 1-Deoxy-1-fluoro-α-D-glucopyranose; Glucopyranosyl Fluoride; Fluoroglucose; α-Glucosyl Fluoride; 1-Fluoro-D-glucose
EINECS	218-267-6

Quality Control

Our Glucosyl Fluoride is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity, suitable for research and development applications. While specific grades (e.g., Research, High-Purity) are available, all materials are characterized by techniques including NMR, HPLC, and MS to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent decomposition. For long-term storage, consider using a desiccator.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (NMR)	Conforms
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.