Description

(R)-(+)-Canadine CAS NO 2086-96-6 is a naturally occurring isoquinoline alkaloid, specifically the (R)-(+)-enantiomer of canadine, known for its distinct stereochemistry and biological activity. This compound serves as a crucial chiral building block and reference standard in advanced pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical synthesis sectors for applications ranging from drug discovery to process chemistry.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of complex bioactive molecules and potential therapeutic agents.
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate biological pathways and receptor interactions.
• Asymmetric Synthesis: Employed as a chiral ligand or catalyst in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Natural Product Chemistry: Serves as a benchmark for the isolation, identification, and characterization of related alkaloids in plant extracts.
• Analytical Standard: Provides a high-purity standard for method development and quality control in analytical laboratories using HPLC, LC-MS, or NMR.

Basic Information

Product Name	(R)-(+)-Canadine
CAS No.	2086-96-6
Molecular Formula	C20H21NO4
Molecular Weight	339.39 g/mol
Synonyms	(R)-Canadine; (+)-Canadine; (R)-(+)-Tetrahydroberberine; (R)-5,6,13,13a-Tetrahydro-9,10-dimethoxy-6-methyl-[1,3]benzodioxolo[5,6-c]-2H-isoquinolino[2,1-b]isoquinoline; (R)-Xylopinine; NSC 51046; Canadine, (R)-(+)-
EINECS	Contact for details

Quality Control

Our (R)-(+)-Canadine is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.