Description

Meclocycline is a semisynthetic tetracycline antibiotic derived from oxytetracycline, known for its broad-spectrum antibacterial activity. This compound is particularly valued for its efficacy against a wide range of Gram-positive and Gram-negative bacteria, as well as certain atypical pathogens. It is primarily utilized in the pharmaceutical and research sectors for the development of topical formulations and as a critical reference standard in analytical chemistry.

Application

• Pharmaceutical Active Ingredient (API): Used in the formulation of topical creams, ointments, and gels for the treatment of skin infections, including acne vulgaris.
• Veterinary Medicine: Employed in topical preparations for treating bacterial infections in animals.
• Biochemical Research: Serves as a key reference standard and inhibitor in microbiological and pharmacological studies to investigate bacterial protein synthesis and resistance mechanisms.
• Analytical Chemistry: Used as a certified reference material (CRM) for quality control and method validation in HPLC and other analytical techniques.
• Cosmeceutical Development: Incorporated into advanced skincare products targeting acne-prone skin due to its antibacterial and anti-inflammatory properties.

Basic Information

Product Name	Meclocycline
CAS No.	2013-58-3
Molecular Formula	C22H21ClN2O8
Molecular Weight	476.87 g/mol
Synonyms	Meclocycline; 7-Chloro-6-demethyl-6-deoxytetracycline; 6-Deoxy-6-demethyl-6-methylene-5-oxytetracycline; NSC-112682; Antibiotic U-24729A; SQ 15860; Meclocycline sulfosalicylate (salt form)
EINECS	217-933-9

Quality Control

Our Meclocycline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by IR spectroscopy, purity determination by HPLC, and control of related substances and residual solvents. A Certificate of Analysis (COA) detailing all test results against established specifications is provided with every shipment to ensure traceability and compliance with customer and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.