Description

Galβ(1-3)[Neu5Acα(2-6)]Galnac-β-Pnp CAS NO 1984814-42-7 is a specialized synthetic glycoside, specifically a p-nitrophenyl (PNP) glycoside derivative of a sialylated core 1 O-glycan structure. This compound serves as a critical enzymatic substrate for the study and characterization of glycosyltransferases, glycosidases, and other carbohydrate-active enzymes. It is an essential tool for researchers in glycobiology, enzymology, and pharmaceutical development, enabling the investigation of glycan biosynthesis pathways and the screening of enzyme inhibitors.

Application

• Enzymatic Substrate for Glycosidase Assays: Used as a chromogenic substrate (p-nitrophenol release) for kinetic studies and activity profiling of specific glycosidases, including neuraminidases (sialidases) and β-galactosidases.
• Glycosyltransferase Research: Acts as an acceptor substrate to study the activity and specificity of glycosyltransferases involved in O-glycan elongation and sialylation.
• High-Throughput Screening (HTS): Employed in the development of colorimetric or fluorometric assays for drug discovery campaigns targeting carbohydrate-processing enzymes.
• Biochemical Reagent: Utilized in the synthesis of more complex glycoconjugates or as a standard in analytical methods like HPLC and mass spectrometry for glycan analysis.
• Diagnostic Kit Development: Serves as a key component in the formulation of diagnostic kits for enzyme deficiency disorders or pathogen detection (e.g., influenza neuraminidase activity).

Basic Information

Item	Details
Product Name	Galβ(1-3)[Neu5Acα(2-6)]Galnac-β-Pnp
CAS No.	1984814-42-7
Molecular Formula	C31H43N3O19
Molecular Weight	761.69 g/mol
Synonyms	Phenyl 2-acetamido-2-deoxy-3-O-{β-D-galactopyranosyl-1,3)-6-O-[5-acetamido-3,5-dideoxy-D-glycero-α-D-galacto-non-2-ulopyranosylonic acid]-α-D-galactopyranoside; Sialyl T antigen PNP glycoside; Neu5Acα2-6(Galβ1-3)GalNAc-α-pNP; 6'-Sialyl-N-acetyllactosamine PNP derivative; p-Nitrophenyl 6'-sialyllactosaminide analog; Glycosidase substrate 1984814-42-7; Sialylated core 1 O-glycan PNP
EINECS	Contact for details

Quality Control

Every batch of Galβ(1-3)[Neu5Acα(2-6)]Galnac-β-Pnp is produced and analyzed under strict quality protocols. Our products undergo rigorous purity verification using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural integrity and batch-to-batch consistency suitable for sensitive biochemical research. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.