Description

Biotin-Nh(Peg4-Acid)2 is a high-purity, heterobifunctional PEG linker featuring a biotin group and two carboxylic acid termini. This compound is essential for creating stable, site-specific conjugations in advanced bioconjugation and drug delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing targeted therapeutics, affinity purification matrices, and sophisticated assay platforms.

Application

• Development of antibody-drug conjugates (ADCs) and other targeted biopharmaceuticals.
• Functionalization of surfaces and nanoparticles for biosensor and diagnostic assay development.
• Synthesis of affinity chromatography media for the purification of recombinant proteins.
• Creation of PEGylated constructs to improve pharmacokinetic properties of therapeutic molecules.
• Site-specific labeling of proteins, peptides, and oligonucleotides for imaging and tracking studies.
• Crosslinking agent in the preparation of hydrogels and other biomaterials.

Basic Information

Product Name	Biotin-Nh(Peg4-Acid)2
CAS No.	1964503-35-2
Molecular Formula	C33H58N4O14S
Molecular Weight	766.90 g/mol
Synonyms	Biotin-PEG4-acid, Biotin-PEG4-COOH; Biotinamido-PEG4-acid; 2-[2-[2-[2-[2-[5-[(3aS,4S,6aR)-2-Oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]acetic acid; Biotin-PEG4-Propionic Acid; Biotin-PEG4-CH2CH2COOH; Biotinylated PEG linker
EINECS	Contact for details

Quality Control

Our Biotin-Nh(Peg4-Acid)2 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. Each lot is accompanied by comprehensive analytical data, including HPLC, NMR, and MS. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.