Description

Pc Biotin-Peg3-Azide CAS NO 1937270-46-6 is a specialized bifunctional linker molecule designed for advanced bioconjugation and click chemistry applications. Its core value lies in combining the high-affinity biotin-streptavidin binding system with a flexible polyethylene glycol (PEG) spacer and a terminal azide group for copper-catalyzed azide-alkyne cycloaddition (CuAAC). This product is essential for researchers and manufacturers in the fields of proteomics, drug discovery, and diagnostic assay development, enabling precise labeling, immobilization, and cross-linking of biomolecules.

Application

• Bioconjugation Reagent: For site-specific labeling of proteins, antibodies, and peptides with biotin tags for detection or purification.
• Click Chemistry Building Block: Utilized in CuAAC reactions to conjugate biomolecules to alkyne-functionalized surfaces, nanoparticles, or other polymers.
• Proteomics Research: Used in pull-down assays and affinity chromatography to isolate and study protein complexes.
• Diagnostic Kit Development: A key component in the fabrication of biosensors and immunoassays requiring stable and specific immobilization layers.
• ADC (Antibody-Drug Conjugate) Development: Serves as a linker in the construction of novel biotherapeutics, connecting cytotoxic payloads to targeting antibodies.
• Materials Science: Functionalization of surfaces and nanomaterials for creating bioactive interfaces.
• Chemical Biology Probes: Synthesis of activity-based probes for enzyme profiling and target identification.

Basic Information

Product Name	Pc Biotin-Peg3-Azide
CAS No.	1937270-46-6
Molecular Formula	C24H41N7O6S
Molecular Weight	555.70 g/mol
Synonyms	Biotin-PEG3-Azide; Biotin-PEG3-N3; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)pentanamide; N-(2-(2-(2-Azidoethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotin-PEG3-N3 Linker; Biotinylated PEG Azide; Azido-PEG3-Biotin
EINECS	Contact for details

Quality Control

Our Pc Biotin-Peg3-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support research and development requiring high-purity, well-characterized biochemical reagents.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.