Description

Suc-Leu-Leu-Val-Tyr-Pna CAS NO 1926163-44-1 is a synthetic peptide substrate designed for protease activity assays. This compound serves as a critical tool for biochemical research, enabling the precise measurement of proteolytic enzyme kinetics and inhibition. It is primarily utilized by pharmaceutical R&D teams, academic biochemistry laboratories, and diagnostic kit manufacturers focused on enzyme characterization and drug discovery.

Application

• Protease Enzyme Assays: Used as a chromogenic substrate for the kinetic analysis of various serine and cysteine proteases.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and characterize novel protease inhibitors.
• Biochemical Research: Facilitates the study of enzyme mechanisms, substrate specificity, and catalytic efficiency in purified systems.
• Diagnostic Development: Acts as a key reagent in the development of clinical diagnostic tests for conditions linked to abnormal protease activity.
• Quality Control in Biologics: Used to monitor the activity and consistency of enzyme-based therapeutic products during manufacturing.

Basic Information

Product Name	Suc-Leu-Leu-Val-Tyr-Pna
CAS No.	1926163-44-1
Molecular Formula	C35H49N7O9
Molecular Weight	711.82 g/mol
Synonyms	Suc-LLVY-PNA; N-Succinyl-Leu-Leu-Val-Tyr-7-amido-4-methylcoumarin; Suc-Leu-Leu-Val-Tyr-AMC; N-Succinyl-L-leucyl-L-leucyl-L-valyl-L-tyrosine 7-amido-4-methylcoumarin; Protease Substrate Suc-LLVY-PNA; Calpain Substrate I; Suc-LLVY-AMC; CAS 1926163-44-1
EINECS	Contact for details

Quality Control

Our Suc-Leu-Leu-Val-Tyr-Pna is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.