Description

Biotin-Peg2-Azide CAS NO 1910803-72-3 is a high-purity, heterobifunctional crosslinking reagent designed for advanced bioconjugation and click chemistry applications. This compound is critical for researchers and manufacturers who require precise, stable, and efficient labeling of biomolecules, such as proteins and antibodies, for diagnostic and therapeutic development. It is an essential tool for professionals in pharmaceutical R&D, proteomics, and the development of targeted drug delivery systems and diagnostic assays.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Used as a key linker to attach cytotoxic payloads or fluorescent probes to monoclonal antibodies via strain-promoted azide-alkyne cycloaddition (SPAAC) click chemistry.
• Proteomics and Biomarker Discovery: Enables site-specific labeling and pull-down assays for the isolation, identification, and study of protein-protein interactions.
• Diagnostic Assay Development: Facilitates the creation of highly sensitive diagnostic tools, such as ELISA and lateral flow assays, by conjugating detection molecules to solid supports or reporter systems.
• Cell Surface Engineering and Imaging: Allows for the specific labeling of cell surface receptors or glycans for live-cell imaging, flow cytometry, and tracking studies.
• Nanoparticle and Liposome Functionalization: Serves as a critical component for modifying the surface of drug delivery vehicles to achieve targeted delivery to specific tissues or cells.
• Materials Science and Biointerface Engineering: Used to create bioactive surfaces and hydrogels with tailored properties for tissue engineering and biosensor applications.

Basic Information

Product Name	Biotin-Peg2-Azide
CAS No.	1910803-72-3
Molecular Formula	C₂₀H₃₄N₆O₅S
Molecular Weight	470.59 g/mol
Synonyms	5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-azidoethoxy)ethoxy)ethyl)pentanamide; Biotin-PEG2-N3; Biotin-PEG₂-Azide; Biotin-PEG2-Azide; N-(2-(2-(2-Azidoethoxy)ethoxy)ethyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide; Biotin-PEG₂-N₃; Biotin-(PEG)₂-azide; Azido-PEG2-Biotin
EINECS	Contact for details

Quality Control

Our Biotin-Peg2-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.