Description

6-Chloro-4-Methylumbelliferyl α-L-Fucopyranoside is a specialized fluorogenic substrate designed for the sensitive detection and quantification of α-L-fucosidase enzyme activity. This compound matters because it provides researchers and diagnostic developers with a highly specific and reliable tool for enzymatic assays, crucial for biochemical research and clinical diagnostics. It is primarily needed by biotechnology firms, pharmaceutical R&D laboratories, and diagnostic kit manufacturers focused on lysosomal storage disorders, cancer biomarker research, and glycobiology studies.

Application

• Enzymatic Assay Substrate: Primary fluorogenic substrate for the detection and kinetic study of α-L-fucosidase activity in vitro.
• Diagnostic Development: Key component in the development of clinical diagnostic kits for conditions like fucosidosis, a lysosomal storage disease.
• Biochemical Research: Used in glycobiology research to study fucosylation processes, cell surface interactions, and carbohydrate metabolism.
• Pharmaceutical Screening: Employed in high-throughput screening (HTS) assays to identify potential inhibitors or modulators of α-L-fucosidase for drug discovery.
• Cancer Biomarker Studies: Utilized in assays to investigate altered fucosidase activity associated with certain cancers and other diseases.
• Quality Control Reagent: Serves as a reference standard or critical reagent in the quality control of diagnostic enzymes and related products.

Basic Information

Product Name	6-Chloro-4-Methylumbelliferyl α-L-Fucopyranoside
CAS No.	1867162-11-5
Molecular Formula	C16H17ClO8
Molecular Weight	372.75 g/mol
Synonyms	6-Chloro-4-methylumbelliferyl α-L-fucopyranoside; 4-MU-α-L-Fuc(6-Cl); α-L-Fucosidase substrate (6-chloro-4-methylumbelliferyl); 6-Chloro-4-MU-α-L-Fuc; (2R,3S,4S,5R,6S)-2-(6-Chloro-4-methyl-2-oxo-2H-chromen-7-yl)oxy-6-methyloxane-3,4,5-triol; Fluorogenic α-L-fucosidase substrate; 6-Cl-4-MU-α-L-Fucopyranoside
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-Methylumbelliferyl α-L-Fucopyranoside is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity, suitable for sensitive research and diagnostic applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Specific Rotation	Contact for details
Fluorogenic Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.