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Fluorescein-Peg3-(n-Boc)-Amine CAS NO 1807534-77-5


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CAS No.:1807534-77-5

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Fluorescein-Peg3-(n-Boc)-Amine is a high-purity, bifunctional chemical linker featuring a fluorescein fluorophore, a triethylene glycol (PEG3) spacer, and a Boc-protected amine group. This compound is critically important for creating stable, fluorescently labeled conjugates in bioconjugation and diagnostic assay development. It is primarily needed by researchers and manufacturers in the fields of biopharmaceuticals, in vitro diagnostics (IVD), and proteomics for tagging antibodies, peptides, and other biomolecules.

Application

  • Bioconjugation Reagent: For site-specific fluorescent labeling of proteins, antibodies, and peptides.
  • Diagnostic Probe Synthesis: A key intermediate in the development of fluorescent probes and assay components for ELISA, flow cytometry, and immunohistochemistry.
  • Biomaterial Functionalization: Used to introduce fluorescent tags and amine handles onto nanoparticles, polymers, and surfaces for tracking and further modification.
  • Drug Delivery Research: Employed in the synthesis of fluorescent drug conjugates to study pharmacokinetics and cellular uptake.
  • Life Science Research: A versatile tool for fluorescence microscopy, cell imaging, and molecular tracking experiments.
  • Chemical Biology: Facilitates the study of biomolecular interactions and pathways through fluorescent tagging.

Basic Information

Product Name Fluorescein-Peg3-(n-Boc)-Amine
CAS No. 1807534-77-5
Molecular Formula C34H38N2O11
Molecular Weight 650.68 g/mol
Synonyms 5-FAM-PEG3-Boc-amine; Fluorescein-PEG3-t-butyloxycarbonyl-amine; 5-Carboxyfluorescein-PEG3-Boc-NH2; Boc-NH-PEG3-5-FAM; 6-((2-(2-(3-((tert-Butoxycarbonyl)amino)propoxy)ethoxy)ethoxy)carbonyl)spiro[isobenzofuran-1(3H),9'-[9H]xanthen]-3-one; 5(6)-Carboxyfluorescein-PEG3-Boc-amine; Boc-amine-PEG3-5-FAM; tert-Butyl N-[3-[2-[2-(2-{[(6-oxido-3-oxo-3H-spiro[2-benzofuran-1,9'-xanthene]-5-yl)carbonyl]amino}ethoxy)ethoxy]ethoxy]propyl]carbamate
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Quality Control

Our Fluorescein-Peg3-(n-Boc)-Amine is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and diagnostic applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemicals and can provide material for GMP-grade applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item Specification
Appearance Orange to red solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95%
Single Isomer Content (HPLC) ≥ 90%
Water Content (KF) ≤ 1.0%
Solubility Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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