Description

5-Tamra-Amyloid β-Protein (1-40) is a fluorescently labeled peptide derivative of the amyloid beta protein, a key biomarker in Alzheimer's disease research. This compound is specifically engineered for advanced fluorescence-based detection and imaging applications, offering high sensitivity and specificity. It is an essential reagent for researchers and diagnostic developers in the fields of neurodegenerative disease research, in vitro diagnostics (IVD), and high-throughput screening for therapeutic agents.

Application

• Biomarker Research & Assay Development: Used as a fluorescent tracer in ELISA, Western blot, and other immunoassays to study amyloid beta aggregation and clearance.
• In Vitro Diagnostics (IVD): Serves as a critical component in the development of diagnostic kits for the detection of amyloid beta peptides in biological samples.
• High-Content Screening (HCS): Enables fluorescent labeling in cellular and biochemical assays for drug discovery targeting amyloid pathways.
• Fluorescence Microscopy & Imaging: Provides a powerful tool for visualizing amyloid beta localization and plaque formation in cell-based and tissue models.
• Protein-Protein Interaction Studies: Facilitates Förster Resonance Energy Transfer (FRET) and other biophysical techniques to investigate molecular interactions involving amyloid beta.
• Quality Control & Reference Standard: Acts as a characterized reference material for calibrating analytical instruments and validating assay performance in pharmaceutical QC labs.

Basic Information

Product Name	5-Tamra-Amyloid β-Protein (1-40)
CAS No.	1802087-81-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5-TAMRA-Amyloid β (1-40); TAMRA-Aβ (1-40); 5-Carboxytetramethylrhodamine labeled Amyloid Beta Protein (1-40); Fluorescent Amyloid Beta Peptide; Aβ1-40-TAMRA; Amyloid β-Peptide (1-40) 5-TAMRA conjugate; 5-TAMRA-Aβ40
EINECS	Contact for details

Quality Control

Our 5-Tamra-Amyloid β-Protein (1-40) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and performance for critical research and diagnostic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	Red to purple solid or lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70% (by weight)
Extinction Coefficient	Contact for details
Fluorescence Properties	Ex/Em ~ 546/579 nm
Solubility	Soluble in DMSO, DMF, or aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.