Description

n-Benzyl Epinephrine-D3 is a deuterium-labeled analog of n-benzyl epinephrine, a key chemical intermediate. This compound is specifically designed for use as an internal standard in quantitative analytical methods, providing superior accuracy and reliability in complex matrices. It is essential for researchers and quality control laboratories in the pharmaceutical and biotechnology sectors who require precise measurement of epinephrine derivatives for method development, pharmacokinetic studies, and impurity profiling.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of epinephrine analogs.
• Critical reagent in pharmaceutical research and development for studying drug metabolism and pharmacokinetics (DMPK).
• Used in bioanalytical method development and validation to ensure accuracy, precision, and regulatory compliance (e.g., FDA, EMA guidelines).
• Application in clinical diagnostics for the development of high-sensitivity assays for catecholamines and related metabolites.
• Tool compound in metabolomics and proteomics research for pathway analysis and biomarker discovery.
• Reference material for quality control and stability testing of active pharmaceutical ingredients (APIs) and finished drug products.

Basic Information

Product Name	n-Benzyl Epinephrine-D3
CAS No.	1795027-87-0
Molecular Formula	C₁₇H₁₆D₃NO₃
Molecular Weight	~285.35 g/mol
Synonyms	Deuterated n-Benzyl Epinephrine; 4-[1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol-α,α,β-D3 Benzyl Ether; 3,4-Dihydroxy-α-[(methylamino)methyl]-D3-benzyl alcohol Benzyl Ether; Benzylarterenol-D3; N-Benzylnorepinephrine-D3; Deuterium Labeled NBE; (R)-n-Benzyl Epinephrine-D3
EINECS	Contact for details

Quality Control

Our n-Benzyl Epinephrine-D3 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and determination of isotopic enrichment. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes batch-specific data on purity, chemical identity, and deuterium content. Our quality commitment ensures the material meets the stringent requirements for use in regulated analytical and research environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D3)	≥ 98 atom % D
Chemical Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.