Description

Salbutamol Dimer-D18 is a deuterium-labeled internal standard critical for precise quantitative analysis in mass spectrometry. This high-purity reference material is essential for ensuring accuracy and reproducibility in bioanalytical studies, particularly for pharmacokinetic and metabolic research. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers specializing in LC-MS/MS method development and validation for Salbutamol and related compounds.

Application

• Internal Standard for LC-MS/MS: Used as a deuterated internal standard for the accurate quantification of Salbutamol in complex biological matrices such as plasma, serum, and urine.
• Pharmacokinetic Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Bioanalytical Method Development: Serves as a critical component in developing and validating robust, sensitive, and selective analytical methods compliant with FDA and ICH guidelines.
• Metabolite Identification & Profiling: Aids in the identification and quantification of Salbutamol metabolites, supporting drug safety and efficacy evaluations.
• Doping Control Analysis: Employed in sports anti-doping laboratories for the definitive confirmation and precise measurement of Salbutamol, a β-2 agonist subject to therapeutic use exemptions.
• Quality Control in Pharmaceutical Manufacturing: Supports in-process testing and final product release testing for Salbutamol-based pharmaceutical formulations.

Basic Information

Product Name	Salbutamol Dimer-D18
CAS No.	1794793-26-2
Molecular Formula	C26H30D18N2O7
Molecular Weight	~ 494.7 g/mol
Synonyms	Albuterol Dimer-D18; (RS)-1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-2-[(1,1-dimethylethyl)amino]ethanol Dimer-D18; Salbutamol-d18 Dimer; Deuterated Salbutamol Dimer Internal Standard; 2-(tert-Butylamino)-1-(4-hydroxy-3-hydroxymethylphenyl)ethanol Dimer-D18
EINECS	Contact for details

Quality Control

Every batch of Salbutamol Dimer-D18 is manufactured and tested under strict quality management systems. We provide comprehensive analytical data to support your regulatory submissions, including Certificates of Analysis (COA) with detailed results for identity, purity (HPLC), chemical purity, and isotopic enrichment. Our quality commitment aligns with the standards expected for high-purity reference standards used in GLP/GMP-compliant environments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chemical Purity	≥ 95.0%
Isotopic Enrichment	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.