Description

Biotin-Peg3-Oxyamine CAS NO 1786206-22-1 is a high-purity, heterobifunctional crosslinking reagent featuring a biotin moiety, a triethylene glycol (PEG3) spacer, and an oxyamine functional group. This compound is engineered for the site-specific conjugation of biomolecules, enabling the creation of stable, biotinylated complexes for advanced detection and purification workflows. It is an essential tool for researchers and manufacturers in bioconjugation, proteomics, and diagnostic assay development, where precise labeling and high-affinity capture are critical.

Application

• Bioconjugation Reagent: For the site-specific labeling of aldehydes and ketones on proteins, antibodies, and other biomolecules via oxime ligation.
• Affinity Probe Development: Creation of biotinylated ligands, peptides, or small molecules for pull-down assays and target identification.
• Diagnostic Assay Components: Used in the synthesis of detection conjugates for ELISA, lateral flow assays, and other immunoassay platforms.
• Surface Functionalization: Immobilization of biomolecules onto sensor chips (e.g., SPR, quartz crystal microbalance) or solid supports for biosensing.
• Protein and Cell Capture: Facilitating streptavidin/avidin-based purification and isolation of tagged complexes in proteomics research.
• Drug Delivery System Research: As a building block for constructing targeted delivery conjugates where biotin acts as a targeting or tracking moiety.

Basic Information

Product Name	Biotin-Peg3-Oxyamine
CAS No.	1786206-22-1
Molecular Formula	C₂₀H₃₈N₄O₇S
Molecular Weight	478.60 g/mol
Synonyms	Biotin-PEG3-oxyamine; Biotin-PEG3-aminooxy; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-(aminooxy)ethoxy)ethoxy)ethyl)pentanamide; Aminooxy-PEG3-biotin; Biotinamidocaproyl-PEG3-aminooxy; Biotin-PEG3-ONH₂; Biotinylated PEG3 aminooxy; Oxyamine-PEG3-biotin
EINECS	Contact for details

Quality Control

Our Biotin-Peg3-Oxyamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure identity, potency, and consistency. Certificates of Analysis (COA) with detailed specifications are provided to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and easily oxidized nature. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.