Description

3,6,9,12,15-Pentaoxahexadecan-1-Ol,16-(4-Methylphenyl)-,1-(4-Methylbenzenesulfonate) is a specialized, high-purity chemical intermediate featuring a unique polyether chain linked to a tosylate ester. This compound matters for its role as a versatile building block in advanced organic synthesis, enabling the controlled introduction of hydrophilic spacer groups. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty polymer industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Used in the synthesis of prodrugs, drug conjugates, and active pharmaceutical ingredients (APIs) requiring polyethylene glycol (PEG)-like linkers for enhanced solubility or bioavailability.
• Polymer Chemistry: Serves as a functional monomer or cross-linking agent for creating specialty polymers with tailored hydrophilicity, such as hydrogels, non-ionic surfactants, and coatings.
• Bioconjugation: Acts as a key reagent for attaching molecules (e.g., dyes, proteins, targeting ligands) to nanoparticles or other biological entities via its reactive tosylate group.
• Material Science: Employed in surface modification and the development of advanced materials where controlled surface energy and compatibility are critical.
• Agrochemical Synthesis: Utilized as an intermediate in creating novel surfactants, adjuvants, or active compounds with specific solubility profiles.
• Research & Development: A valuable tool for academic and industrial research exploring new chemical entities and reaction pathways involving polyether chains.

Basic Information

Item	Details
Product Name	3,6,9,12,15-Pentaoxahexadecan-1-Ol,16-(4-Methylphenyl)-,1-(4-Methylbenzenesulfonate)
CAS No.	1688666-69-4
Molecular Formula	C29H44O9S
Molecular Weight	568.72 g/mol
Synonyms	16-(4-Methylphenyl)-3,6,9,12,15-pentaoxahexadecan-1-ol 1-(4-methylbenzenesulfonate); PEG5 Tosylate Derivative; Tetraethylene Glycol Monomethyl Ether p-Toluenesulfonate Ester; 2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl 4-methylbenzenesulfonate; mPEG5-OTs; Poly(ethylene glycol) methyl ether tosylate (average Mn 250); 4-Methylbenzenesulfonic acid 2-[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethoxy]ethyl ester
EINECS	Contact for details

Quality Control

Our 3,6,9,12,15-Pentaoxahexadecan-1-Ol,16-(4-Methylphenyl)-,1-(4-Methylbenzenesulfonate) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) documenting purity, assay, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to the tosylate ester functionality, the material should be kept under an inert atmosphere if long-term storage is anticipated to prevent potential hydrolysis.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.