Description

2,5-Dioxo-1-(4-(Pyridin-2-Yldisulfanyl)Butanoyloxy)Pyrrolidine-3-Sulfonic Acid is a specialized heterocyclic compound featuring a disulfide linker and a sulfonic acid group, making it a valuable intermediate for advanced chemical synthesis. This compound matters for its role in creating functionalized molecules, particularly in the development of bioconjugates and materials with tailored reactivity. Pharmaceutical researchers and fine chemical manufacturers need it for applications in drug discovery, proteomics, and the synthesis of novel polymers.

Application

• Bioconjugation Reagent: Used for site-specific protein and peptide modification via its cleavable disulfide linkage.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) and prodrugs.
• Crosslinking Agent: Employed in polymer chemistry and material science to create hydrogels or functionalized surfaces.
• Proteomics Research: Acts as a tool compound for studying protein interactions and labeling.
• Chemical Biology Probes: Utilized in the development of probes for enzyme activity or cellular imaging.
• Linker for Solid-Phase Synthesis: Applied in peptide and oligonucleotide synthesis on solid supports.

Basic Information

Product Name	2,5-Dioxo-1-(4-(Pyridin-2-Yldisulfanyl)Butanoyloxy)Pyrrolidine-3-Sulfonic Acid
CAS No.	1628113-16-5
Molecular Formula	C14H15N3O7S3
Molecular Weight	433.48 g/mol
Synonyms	1-(4-(Pyridin-2-yldisulfanyl)butanoyloxy)-2,5-dioxopyrrolidine-3-sulfonic acid; 3-Sulfopyrrolidine-1,2,5-trione 1-[4-(2-pyridyldithio)butanoate]; Py-ss-butyrate-OSu sulfonate; N-Hydroxysuccinimide ester of 4-(2-pyridyldithio)butanoic acid sulfonate derivative; SPPB sulfonic acid; Disulfide-linked NHS ester sulfonate; 4-(2-Pyridinyldithio)butanoic acid N-succinimidyl ester sulfonic acid; Bioconjugation linker with sulfonate group
EINECS	Contact for details

Quality Control

Our 2,5-Dioxo-1-(4-(Pyridin-2-Yldisulfanyl)Butanoyloxy)Pyrrolidine-3-Sulfonic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C (refrigerated) or as indicated on the label or COA. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Keep container tightly sealed in a desiccated environment after opening.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.