Description

1,5-Difluoro-3-Methyl-2,4-Dinitrobenzene is a high-purity, multi-functional aromatic intermediate characterized by its unique substitution pattern of fluorine and nitro groups. This compound is valued for its role as a versatile building block in advanced organic synthesis, enabling the introduction of specific functionalities into complex molecular architectures. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting new therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and pesticides, leveraging its fluorine and nitro groups for bioactivity.
• Material Science Research: Serves as a precursor for developing specialty polymers, liquid crystals, and advanced organic electronic materials due to its electron-deficient aromatic core.
• Dye and Pigment Intermediate: Employed in the synthesis of complex, high-performance dyes and pigments where fluorine substitution enhances lightfastness and chemical stability.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) for creating biaryl structures.
• Nucleophilic Aromatic Substitution: The activated nitro and fluoro groups make it an excellent electrophile for nucleophilic substitution reactions to introduce diverse amines, alkoxides, and thiols.

Basic Information

Product Name	1,5-Difluoro-3-Methyl-2,4-Dinitrobenzene
CAS No.	1616526-79-4
Molecular Formula	C7H4F2N2O4
Molecular Weight	218.12 g/mol
Synonyms	2,4-Dinitro-1,5-difluoro-3-methylbenzene; 3-Methyl-2,4-dinitro-1,5-difluorobenzene; 1,5-Difluoro-3-methyl-2,4-dinitrobenzene; Benzene, 1,5-difluoro-3-methyl-2,4-dinitro-; 2,4-Dinitro-3-methyl-1,5-difluorobenzene
EINECS	Contact for details

Quality Control

Our 1,5-Difluoro-3-Methyl-2,4-Dinitrobenzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), impurity profile, and physical characteristics. Our quality commitment ensures the material meets the stringent requirements for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.