Description

(R)-n-((R)-1-(2-Chlorophenyl)Ethyl)-2-Methylpropane-2-Sulfinamide CAS NO 1588938-65-1 is a high-purity chiral sulfinamide building block, a critical intermediate in modern asymmetric synthesis. Its primary value lies in enabling the stereoselective construction of complex molecules, particularly in pharmaceutical development. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require reliable, high-quality chiral auxiliaries and intermediates.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and cardiovascular drug candidates.
• Asymmetric Synthesis: Acts as a versatile chiral auxiliary or ligand in stereoselective reactions, including nucleophilic additions to imines and asymmetric reductions.
• Agrochemical Research: Used in the development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Catalyst Development: Serves as a precursor or component in the design of novel chiral catalysts for industrial-scale enantioselective transformations.
• Academic & Process R&D: A valuable tool for methodology development in academic laboratories and for scaling up chiral synthetic routes in process chemistry.
• Fine Chemical Production: Intermediate for the manufacture of specialty chemicals requiring high enantiomeric purity.

Basic Information

Product Name	(R)-n-((R)-1-(2-Chlorophenyl)Ethyl)-2-Methylpropane-2-Sulfinamide
CAS No.	1588938-65-1
Molecular Formula	C₁₂H₁₈ClNOS
Molecular Weight	259.79 g/mol
Synonyms	(R,R)-2-Methyl-N-[(1R)-1-(2-chlorophenyl)ethyl]propane-2-sulfinamide; (R)-N-[(1R)-1-(2-Chlorophenyl)ethyl]-2-methylpropane-2-sulfinamide; (R,R)-N-(1-(2-Chlorophenyl)ethyl)-2-methylpropane-2-sulfinamide; tert-Butanesulfinamide, N-[(1R)-1-(2-chlorophenyl)ethyl]-, (R)-; Chiral Sulfinamide Intermediate; (R,R)-2-Chloro-α-methylbenzenemethanamine N-tert-butylsulfinyl deriv.
EINECS	Contact for details

Quality Control

Our (R)-n-((R)-1-(2-Chlorophenyl)Ethyl)-2-Methylpropane-2-Sulfinamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) and purity assessment, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.