Description

Folic Acid Sulfosuccinimidyl Ester Sodium Salt (Technical Grade) is a reactive chemical derivative of folic acid, specifically designed for bioconjugation applications. This compound is crucial for researchers and manufacturers who require a reliable and efficient method to label or crosslink biomolecules with folate moieties. It is primarily needed by professionals in the life sciences, pharmaceutical development, and diagnostic reagent industries for creating targeted conjugates.

Application

• Bioconjugation Reagent: For the covalent attachment of folic acid to proteins, antibodies, peptides, or nanoparticles to create targeted delivery systems.
• Pharmaceutical Research: Used in the development of folate-receptor targeted drug conjugates for cancer therapy and other therapeutic applications.
• Diagnostic Probe Synthesis: Essential for labeling imaging agents (e.g., fluorescent dyes, radioisotopes) with folate for in vitro and in vivo diagnostic assays.
• Biomaterial Functionalization: Modification of polymer surfaces, hydrogels, or other materials to impart specific cell-targeting properties.
• Life Science Research: A key tool in biochemical and cell biology studies investigating folate receptor-mediated uptake and signaling pathways.
• Immunoassay Development: Conjugation to detection antibodies or antigens in enzyme-linked immunosorbent assay (ELISA) and other immunoassay formats.

Basic Information

Product Name	Folic Acid Sulfosuccinimidyl Ester Sodium Salt (Technical Grade)
CAS No.	1572180-79-0
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Folic Acid NHS Ester Sodium Salt; Folate-NHS Ester Sodium Salt; N-Hydroxysulfosuccinimide Ester of Folic Acid Sodium Salt; Sulfo-NHS-Folate Sodium Salt; Folic Acid, N-succinimidyl ester, sodium derivative; Folic Acid Active Ester; FA-NHS Sulfo Sodium Salt; Vitamin B9 Sulfo-NHS Ester Sodium Salt
EINECS	Contact for details

Quality Control

Our Technical Grade Folic Acid Sulfosuccinimidyl Ester Sodium Salt is produced under a quality management system to ensure batch-to-batch consistency for industrial and research use. While not intended for direct human pharmaceutical application, it is manufactured with high purity standards suitable for conjugation chemistry. Certificates of Analysis (COA) detailing key parameters such as assay, purity, and functional activity are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term stability, consider storage under desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	Yellow to orange powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 90% (Technical Grade)
Water Content	≤ 5.0%
Solubility	Soluble in water, DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.