Description

Vosoritide Acetate CAS NO 1480724-61-5 is a synthetic analog of C-type natriuretic peptide (CNP) designed for therapeutic use. This compound is a critical active pharmaceutical ingredient (API) for the treatment of achondroplasia, the most common form of skeletal dysplasia. It is primarily required by pharmaceutical manufacturers and research institutions engaged in developing and producing targeted therapies for genetic growth disorders and bone-related conditions.

Application

• Pharmaceutical API: Primary active ingredient in the formulation of treatments for achondroplasia.
• Clinical Research: Used in preclinical and clinical studies for evaluating efficacy and safety in skeletal dysplasias.
• Biopharmaceutical Development: Serves as a reference standard and key component in the development of novel peptide-based therapeutics.
• Specialty Medicine Production: Manufacture of injectable solutions for pediatric endocrinology and genetic disorder management.
• Regulatory Submissions: Sourced as a high-purity material for drug master file (DMF) preparation and regulatory compliance documentation.

Basic Information

Item	Details
Product Name	Vosoritide Acetate
CAS No.	1480724-61-5
Molecular Formula	C178H300N56O55 • xC2H4O2
Molecular Weight	~3964.6 g/mol (free base)
Synonyms	BMN 111 Acetate; Vosoritide (Acetate); CNP Analog (Acetate); C-Type Natriuretic Peptide (1-37) (human) Acetate; BMN-111 Acetate; Natriuretic Peptide C (Acetate); Recombinant Human CNP-37 Acetate; Achondroplasia Therapeutic Peptide Acetate
EINECS	Contact for details

Quality Control

Our Vosoritide Acetate is manufactured under strict quality systems suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity and related substances, peptide content determination, and residual solvent analysis. We provide full traceability and support regulatory filings. A comprehensive Certificate of Analysis (COA) confirming compliance with in-house specifications is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, keep desiccated. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0% (by weight)
Acetate Content	5.0% - 12.0%
Single Maximum Impurity	≤ 1.0%
Total Related Substances	≤ 2.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 10.0 EU/mg
Sterility (where applicable)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.