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(R)-3,3'-Bis(3,5-Diisopropylphenyl)-[1,1'-Binapthalene]-2,2'-Diol CAS NO 1435948-31-4
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CAS No.:1435948-31-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(R)-3,3'-Bis(3,5-Diisopropylphenyl)-[1,1'-Binapthalene]-2,2'-Diol CAS NO 1435948-31-4 is a high-value, chiral binaphthol derivative widely recognized as a privileged ligand and catalyst precursor in asymmetric synthesis. Its core value lies in its ability to induce high enantioselectivity in a variety of organic transformations, enabling the production of single-enantiomer compounds critical for advanced materials and pharmaceuticals. This product is essential for R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty fine chemical industries who require reliable, high-purity chiral auxiliaries to develop novel active ingredients and high-performance materials.
Application
- Asymmetric Catalysis: Serving as a key ligand for transition metals (e.g., Rh, Ru, Pd) in enantioselective hydrogenation, C-C bond formation, and oxidation reactions.
- Pharmaceutical Intermediate Synthesis: Critical for constructing chiral centers in the development of active pharmaceutical ingredients (APIs) and drug candidates.
- Agrochemical Production: Used in the synthesis of enantiomerically pure herbicides, fungicides, and plant growth regulators.
- Material Science: Employed in the development of chiral polymers, liquid crystals, and molecular recognition systems.
- Academic & Industrial R&D: A fundamental tool for methodological development in organic chemistry and process optimization in pilot plants.
- Chiral Resolution: Can be utilized in the preparation of chiral stationary phases for analytical or preparative chromatography.
Basic Information
| Product Name | (R)-3,3'-Bis(3,5-Diisopropylphenyl)-[1,1'-Binapthalene]-2,2'-Diol |
| CAS No. | 1435948-31-4 |
| Molecular Formula | C46H48O2 |
| Molecular Weight | 632.87 g/mol |
| Synonyms | (R)-3,3'-Bis(3,5-diisopropylphenyl)-1,1'-binaphthyl-2,2'-diol; (R)-3,3'-Bis(3,5-diisopropylphenyl)-BINOL; (R)-3,3'-Bis(3,5-di-iso-propylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl; (R)-3,3'-Di(3,5-diisopropylphenyl)-BINOL; (R)-3,3'-Bis(3,5-diisopropylphenyl)-H8-BINOL (Note: H8 indicates a partially hydrogenated binaphthyl core, a common variant); (R)-3,3'-Bis(3,5-di-iso-propylphenyl)-[1,1'-binaphthalene]-2,2'-diol; (R)-3,3'-Bis(3,5-diisopropylphenyl)-2,2'-dihydroxy-1,1'-binaphthyl |
| EINECS | Contact for details |
Quality Control
Every batch of our (R)-3,3'-Bis(3,5-Diisopropylphenyl)-[1,1'-Binapthalene]-2,2'-Diol is manufactured and tested under strict quality management systems. We guarantee high chemical and chiral purity to meet the rigorous demands of catalytic and synthetic applications. Certificates of Analysis (COA) detailing identity, purity (HPLC/Chiral HPLC), and specific tests are provided with each shipment to ensure full traceability and compliance with your project specifications.
Storage
Preserve in a tightly closed container, protected from light. For long-term storage, keep under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to prevent oxidation and maintain stability. The container should be stored in a cool, dry, and well-ventilated area.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 98.0% |
| Chiral Purity (Chiral HPLC) | ≥ 99.0% ee |
| Melting Point | Contact for details |
| Loss on Drying | ≤ 0.5% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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