Description

2-Aminopurine (Hydrochloride) is a modified purine nucleobase analog, a key building block in nucleic acid research and medicinal chemistry. Its primary value lies in its ability to act as a fluorescent probe and a mutagenic agent, enabling critical studies in molecular biology and drug discovery. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic reagent sectors.

Application

• Fluorescent Labeling & Probes: Used as a fluorescent marker in nucleic acid hybridization studies and real-time PCR applications.
• Biochemical Research: Serves as a mutagenic base analog to study DNA replication, repair mechanisms, and polymerase fidelity.
• Antiviral & Anticancer Agent Development: Acts as a core scaffold or intermediate in the synthesis of nucleoside analogs for therapeutic applications.
• Diagnostic Reagent Synthesis: Employed in the manufacturing of specialized reagents for molecular diagnostic kits.
• Enzyme Substrate Studies: Utilized to investigate the activity and inhibition of enzymes like adenosine deaminase and various kinases.
• Academic & Industrial R&D: A fundamental tool for basic research in genetics, epigenetics, and chemical biology.

Basic Information

Product Name	2-Aminopurine (Hydrochloride)
CAS No.	1428126-74-2
Molecular Formula	C5H6N6•HCl
Molecular Weight	186.60 g/mol (Free base: 150.14)
Synonyms	2-AP•HCl; 2-Aminohypoxanthine Hydrochloride; 2-Amino-1H-purin-6(7H)-one Hydrochloride; 2-Amino-6-hydroxypurine Hydrochloride; 6-Amino-3H-purin-2-one Hydrochloride; 2-Aminopurine HCl; 2-Aminopurinium Chloride
EINECS	Contact for details

Quality Control

Our 2-Aminopurine (Hydrochloride) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.