Description

(4E, 8E)-Sphingadienine-C18-1-Phosphate is a high-purity, synthetic sphingolipid derivative, specifically a phosphorylated sphingoid base. This compound is a critical biochemical tool and a valuable reference standard for lipidomics research and pharmaceutical development. It is essential for researchers and manufacturers in the life sciences, particularly those focused on sphingolipid metabolism, cell signaling pathways, and drug discovery. The product is supplied with full analytical documentation to ensure reliability and reproducibility in sensitive applications.

Application

• Biochemical Research & Lipidomics: Serves as a key analytical standard for the identification and quantification of sphingolipids in complex biological samples using mass spectrometry (LC-MS/MS).
• Cell Signaling Studies: Used to investigate the role of sphingoid base phosphates in cellular processes such as apoptosis, proliferation, and immune response.
• Pharmaceutical Reference Standard: Employed as a certified reference material (CRM) in the quality control and development of novel therapeutics targeting sphingolipid pathways.
• Enzyme Activity Assays: Acts as a substrate or product in assays for enzymes like sphingosine kinases and phosphatases to study their kinetics and inhibition.
• Cosmeceutical R&D: Investigated for its potential bioactive properties in advanced skincare formulations targeting skin barrier function and cellular communication.

Basic Information

Product Name	(4E, 8E)-Sphingadienine-C18-1-Phosphate
CAS No.	1419705-13-7
Molecular Formula	C18H36NO5P
Molecular Weight	377.46 g/mol
Synonyms	Sphingadienine 1-phosphate; trans,trans-Sphingadienine-1-phosphate; (2S,3R,4E,8E)-2-Amino-3-hydroxyoctadeca-4,8-dien-1-yl dihydrogen phosphate; C18-Sphingadienine-1-P; Sphingadienine phosphate; D-erythro-Sphingadienine-1-phosphate; Phytosphingosine phosphate derivative; Lipid mediator standard
EINECS	Contact for details

Quality Control

Every batch of (4E, 8E)-Sphingadienine-C18-1-Phosphate is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, providing detailed results from NMR, HPLC, and MS analysis to confirm identity, purity, and stability.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under an inert atmosphere. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.