Description

1-Pyrenebutyryl Aminopropyl Methanethiosulfonate is a specialized heterobifunctional crosslinking reagent designed for advanced bioconjugation and labeling applications. This compound is critical for researchers and developers requiring precise, site-specific attachment of pyrene fluorophores or other functional groups to biomolecules. It is primarily utilized in the life sciences sector for creating stable, fluorescently labeled probes, studying protein interactions, and developing diagnostic assays. The product is supplied with a Certificate of Analysis to ensure batch-to-batch consistency and reliability for sensitive experimental work.

Application

• Bioconjugation and Protein Labeling: Site-specific modification of proteins, antibodies, and peptides with pyrene fluorophores for fluorescence spectroscopy (FRET) and microscopy studies.
• Probe Development for Diagnostics: Synthesis of fluorescent probes and tracers used in immunoassays, biosensors, and in vitro diagnostic (IVD) kits.
• Material Surface Functionalization: Modification of nanoparticles, quantum dots, or polymer surfaces to introduce specific reactive groups for downstream biomolecule immobilization.
• Structural Biology Research: Crosslinking agent for studying protein-protein interactions, conformational changes, and molecular distances via pyrene excimer formation.
• Pharmaceutical Research: Tool compound in drug discovery for creating drug-fluorophore conjugates to study drug delivery, targeting, and cellular uptake mechanisms.

Basic Information

Product Name	1-Pyrenebutyryl Aminopropyl Methanethiosulfonate
CAS No.	1391053-24-9
Molecular Formula	C26H25NO3S2
Molecular Weight	463.61 g/mol
Synonyms	N-(3-(Methanethiosulfonyl)propyl)-4-(1-pyrenyl)butanamide; 4-(1-Pyrenyl)-N-[3-[(methylsulfonyl)thio]propyl]butanamide; Pyrenebutyryl MTS; Pyrene-MTS Reagent; Aminopropyl Methanethiosulfonate Pyrenebutyryl Derivative; Heterobifunctional Pyrene Crosslinker; MTS-Pyrene Reagent
EINECS	Contact for details

Quality Control

Our 1-Pyrenebutyryl Aminopropyl Methanethiosulfonate is manufactured under strict quality control protocols to ensure high purity and performance for research applications. Each batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label or COA. Due to its hygroscopic (moisture-sensitive) nature, the container should be sealed under an inert atmosphere after each use and desiccated for long-term storage. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.