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Bis-Aminooxy-Peg7 CAS NO 1383980-52-6


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CAS No.:1383980-52-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis-Aminooxy-Peg7 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring two aminooxy groups, enabling efficient conjugation to carbonyl-containing molecules. This compound is critical for creating stable, site-specific bioconjugates and cross-linked materials with precise control over structure and function. It is primarily needed by researchers and manufacturers in bioconjugation, pharmaceutical development, and advanced material science for applications requiring controlled molecular assembly.

Application

  • Bioconjugation and Protein Modification: Site-specific conjugation of proteins, antibodies, or peptides via their N-terminal or engineered ketone/aldehyde groups.
  • Drug Delivery System Development: Synthesis of PEGylated drug conjugates and linkers for controlled-release formulations.
  • Hydrogel and Biomaterial Cross-linking: Creating biocompatible networks and scaffolds for tissue engineering and 3D cell culture.
  • Surface Functionalization: Immobilization of biomolecules onto sensor chips, nanoparticles, or diagnostic platforms.
  • Antibody-Drug Conjugate (ADC) Linker: Serving as a cleavable or non-cleavable bridge between a cytotoxic payload and a targeting antibody.
  • Oligonucleotide and Small Molecule Conjugation: Attaching labels, probes, or therapeutic agents to oligonucleotides or other carbonyl-containing compounds.

Basic Information

Product Name Bis-Aminooxy-Peg7
CAS No. 1383980-52-6
Molecular Formula C30H62N2O16
Molecular Weight 682.8 g/mol
Synonyms 1,17-Bis(aminooxy)-3,6,9,12,15-pentaoxaheptadecane; α,ω-Bis-O-(amino) PEG7; Bis-aminooxy PEG 7; Aminooxy-PEG7-aminooxy; PEG7 bis(aminooxy); HO-PEG7-ONH2; 3,6,9,12,15-Pentaoxaheptadecane-1,17-diamine, 1,17-dioxy-; Heterobifunctional PEG linker aminooxy-PEG7-aminooxy
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Quality Control

Our Bis-Aminooxy-Peg7 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent performance for critical research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be sealed under an inert atmosphere (e.g., nitrogen or argon) after each use to prevent moisture absorption and degradation. Keep away from strong oxidizing agents.

Specification

Item Specification
Appearance Colorless to pale yellow viscous liquid
Identification (IR) Conforms to structure
Purity (HPLC) ≥ 95%
Water Content (KF) ≤ 1.0%
Molecular Weight Confirmation (MS) Conforms
Functional Group Assay ≥ 90%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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