Description

Biotin-Peg3-Propionic Hydrazide CAS NO 1381861-94-4 is a high-purity, heterobifunctional crosslinking reagent designed for advanced bioconjugation. This compound is critical for creating stable, site-specific linkages between biomolecules, such as antibodies and enzymes, and various probes or solid supports. It is essential for researchers and manufacturers in pharmaceutical development, diagnostic assay production, and proteomics research who require precise and reliable conjugation tools.

Application

• Antibody-Drug Conjugate (ADC) Development: Site-specific conjugation of cytotoxic payloads to monoclonal antibodies for targeted cancer therapies.
• Diagnostic Assay Reagent: Immobilization of proteins or antibodies onto sensor surfaces or microplates for ELISA and other immunoassays.
• Proteomics and Biomarker Discovery: Labeling and enrichment of glycoproteins or other biomolecules for mass spectrometry analysis.
• Affinity Chromatography Ligand Synthesis: Covalent attachment of biotinylated ligands to avidin/streptavidin resins.
• Fluorescent Probe and Nanoparticle Conjugation: Functionalization of imaging agents with biotin for detection and cellular targeting.
• Peptide and Protein Modification: Introduction of biotin tags onto specific sites for purification, detection, or interaction studies.

Basic Information

Product Name	Biotin-Peg3-Propionic Hydrazide
CAS No.	1381861-94-4
Molecular Formula	C₂₀H₃₇N₅O₆S
Molecular Weight	475.60 g/mol
Synonyms	Biotin-PEG3-propionyl hydrazide; Biotinamido-PEG3-propionic hydrazide; (+)-Biotin-PEG3-propionic hydrazide; Biotin-PEG3-CH₂CH₂CONHNH₂; N-(Biotinyl)-3,6,9-trioxaundecanedihydrazide; Biotin-PEG3-C2-hydrazide; Biotinylated PEG hydrazide; Biotin-(PEG)₃-propionic hydrazide
EINECS	Contact for details

Quality Control

Our Biotin-Peg3-Propionic Hydrazide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the stringent requirements for research and biopharmaceutical applications. Certificates of Analysis (COA) with full characterization data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.