Description

Suc-Ile-Glu(γ-Pip)-Gly-Arg-Pna (Hydrochloride) is a synthetic peptide substrate designed for high-specificity enzymatic activity studies. This compound is a critical tool for researchers and developers in the life sciences, enabling precise biochemical assays and diagnostic test development. It is primarily utilized by pharmaceutical R&D teams, diagnostic kit manufacturers, and academic research institutions focusing on protease and peptidase function.

Application

• Protease/Peptidase Activity Assays: Used as a selective chromogenic substrate for the kinetic analysis and characterization of specific serine or cysteine proteases.
• Diagnostic Reagent Development: Serves as a key component in the formulation of in-vitro diagnostic (IVD) kits for clinical testing.
• Drug Discovery Screening: Employed in high-throughput screening (HTS) platforms to identify and evaluate potential enzyme inhibitors for therapeutic development.
• Biochemical Research: Facilitates fundamental studies on enzyme kinetics, substrate specificity, and catalytic mechanisms in academic and industrial laboratories.
• Quality Control in Biologics: Acts as a reference standard or assay component for monitoring the activity and purity of enzyme-based biopharmaceuticals.

Basic Information

Product Name	Suc-Ile-Glu(γ-Pip)-Gly-Arg-Pna (Hydrochloride)
CAS No.	1379822-04-4
Molecular Formula	C36H57N11O11 • HCl
Molecular Weight	848.37 g/mol (free base)
Synonyms	Suc-Ile-Glu(γ-Pip)-Gly-Arg-pNA • HCl; N-Succinyl-Isoleucyl-Glutamyl(γ-Piperidyl)-Glycyl-Arginine p-Nitroanilide Hydrochloride; Protease Substrate 1379822-04-4; Chromogenic Peptide Substrate; Suc-Ile-Glu(γ-Pip)-Gly-Arg-pNA • HCl; pNA Substrate; Peptide-pNA Conjugate Hydrochloride
EINECS	Contact for details

Quality Control

Our Suc-Ile-Glu(γ-Pip)-Gly-Arg-Pna (Hydrochloride) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and diagnostic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Assay (Peptide Content)	≥ 80.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in DMSO, DMF; slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.