Description

S-(2,3,4-Trihydroxybutyl)Mercapturic Acid Methyl Ester (Mixture Of Diastereomers) is a specialized mercapturic acid derivative, a key metabolite class used in biochemical and toxicological research. This compound matters for its role as a high-purity reference standard in the study of metabolic pathways, particularly for glutathione conjugation products. It is essential for researchers and quality control laboratories in the pharmaceutical, biotechnology, and contract research organization (CRO) sectors who require precise analytical standards.

Application

• Biomarker Research: Used as a reference standard for identifying and quantifying mercapturic acid metabolites in biological samples.
• Toxicology Studies: Critical for investigating detoxification pathways and the metabolic fate of xenobiotics via glutathione S-transferase (GST) conjugation.
• Pharmaceutical Development: Serves as an analytical standard in drug metabolism and pharmacokinetics (DMPK) studies for metabolite profiling.
• Clinical Diagnostics: Potential use in developing assays for exposure biomarkers to specific chemicals or environmental toxins.
• Academic Research: A valuable tool in biochemistry and molecular biology laboratories studying phase II metabolism.
• Quality Control: Employed as a certified reference material (CRM) to validate analytical methods like LC-MS/MS in testing laboratories.

Basic Information

Item	Detail
Product Name	S-(2,3,4-Trihydroxybutyl)Mercapturic Acid Methyl Ester (Mixture Of Diastereomers)
CAS No.	1356841-25-2
Molecular Formula	C11H19NO7S
Molecular Weight	309.34 g/mol
Synonyms	N-Acetyl-S-(2,3,4-trihydroxybutyl)-L-cysteine methyl ester; THBMA methyl ester; Mercapturic acid metabolite of butadiene (methyl ester); S-(2,3,4-Trihydroxybutyl)-N-acetylcysteine methyl ester; N-Acetyl-S-(1,2,3,4-tetrahydroxybutyl)-L-cysteine methyl ester; 1-(Methoxycarbonyl)-2-[(2R)-2-acetamido-3-[(2S,3S,4R)-2,3,4-trihydroxybutyl]sulfanyl]propyl]azanium; Butadiene mercapturate methyl ester
EINECS	Contact for details

Quality Control

Our S-(2,3,4-Trihydroxybutyl)Mercapturic Acid Methyl Ester is produced under a strict quality management system. Each batch is characterized and tested using advanced analytical techniques including HPLC, MS, and NMR to ensure identity, purity, and diastereomeric ratio. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all relevant specifications. We support compliance needs for research and development under cGMP-like controls where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to minimize exposure to atmospheric humidity. For long-term storage, consider desiccants or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 95% (Total of diastereomers)
Water Content (KF)	≤ 2.0 %
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.