Description

2-[[[(11-Aminoundecyl)Oxy]Hydroxyphosphinyl]Oxy]-N,N,n-Trimethyl-Ethanaminium Inner Salt is a specialized zwitterionic phospholipid derivative, engineered to provide a unique combination of cationic and anionic functionality within a single molecule. This compound is critical for applications requiring precise surface modification, membrane interaction, and controlled delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel drug delivery platforms, biomimetic coatings, and diagnostic agents.

Application

• Lipid Nanoparticle (LNP) Formulation: As a functional excipient for modulating the surface charge and stability of mRNA and siRNA delivery systems.
• Biomimetic Membrane Research: For constructing stable, functionalized liposomes and vesicles to study cell membrane dynamics and protein-lipid interactions.
• Gene Delivery Vectors: A key component in non-viral transfection reagents to enhance cellular uptake and endosomal escape of genetic material.
• Surface Coating & Functionalization: Used to create zwitterionic, anti-fouling surfaces on medical devices and diagnostic sensors.
• Pharmaceutical Intermediates: Serves as a sophisticated building block for synthesizing targeted prodrugs and advanced therapeutic agents.
• Diagnostic Agent Conjugation: Facilitates the attachment of imaging or targeting moieties to lipid-based carriers for theranostic applications.

Basic Information

Product Name	2-[[[(11-Aminoundecyl)Oxy]Hydroxyphosphinyl]Oxy]-N,N,n-Trimethyl-Ethanaminium Inner Salt
CAS No.	1354620-97-5
Molecular Formula	C₁₉H₄₃N₂O₅P
Molecular Weight	410.53 g/mol
Synonyms	11-((2-(Trimethylammonio)ethoxy)(hydroxy)phosphoryl)oxy)undecylammonium Inner Salt; (11-Aminoundecyl) 2-(Trimethylammonio)ethyl Phosphate Inner Salt; Zwitterionic C11-Aminophospholipid; PC-amine Zwitterion; N,N,N-Trimethyl-2-[[[(11-aminoundecyl)oxy]hydroxyphosphinyl]oxy]ethanaminium Hydroxide Inner Salt; Amino-PC Lipid; Functionalized Phosphocholine Derivative; LNP Helper Lipid Analog
EINECS	Contact for details

Quality Control

Our 2-[[[(11-Aminoundecyl)Oxy]Hydroxyphosphinyl]Oxy]-N,N,n-Trimethyl-Ethanaminium Inner Salt is produced under strict quality management systems. Each batch is characterized and tested to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical and life science research. Comprehensive analytical data, including NMR, HPLC, and MS, is documented in the Certificate of Analysis (COA) provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This material is hygroscopic (moisture-sensitive); ensure containers are sealed under an inert atmosphere after each use to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.