Description

21-[D(+)-Biotinylamino]-4,7,10,13,16,19-Hexaoxaheneicosanoic Acid is a specialized biotin derivative featuring a hydrophilic polyethylene glycol (PEG) spacer arm. This compound is engineered to facilitate the biotinylation of biomolecules, offering enhanced solubility and reduced steric hindrance compared to standard biotinylation reagents. It is a critical intermediate and reagent for researchers and manufacturers in the life sciences sector, particularly for developing diagnostic assays, targeted drug delivery systems, and advanced bioconjugates.

Application

• Biotinylation Reagent: For labeling proteins, antibodies, peptides, and nucleic acids with biotin for detection or purification via streptavidin/avidin binding.
• Diagnostic Assay Development: A key component in the production of ELISA kits, lateral flow tests, and other immunoassays requiring high-sensitivity detection.
• Drug Conjugation & ADC Development: Used to attach biotin tags to therapeutic molecules or linkers in the research and development of biotin-streptavidin based drug delivery platforms.
• Affinity Purification Probes: Creation of immobilized biotinylated ligands for the capture and isolation of specific target molecules.
• Cell Surface Labeling: For tagging membrane proteins or receptors in flow cytometry and microscopy studies.
• Biomaterial Functionalization: Modifying surfaces of nanoparticles, polymers, or chips with biotin for subsequent biomolecular assembly.

Basic Information

Product Name	21-[D(+)-Biotinylamino]-4,7,10,13,16,19-Hexaoxaheneicosanoic Acid
CAS No.	1352814-10-8
Molecular Formula	C31H55N3O10S
Molecular Weight	661.85 g/mol
Synonyms	Biotin-PEG6-COOH; Biotin-PEG6-Acid; Biotinamidohexa(ethylene glycol) carboxylic acid; Biotin-PEG6-propionic acid; 21-(Biotinylamino)-4,7,10,13,16,19-hexaoxaheneicosanoic acid; Biotin-(PEG)6-acid; Biotinylated PEG6 acid; EZ-Link Biotin-PEG6-COOH
EINECS	Contact for details

Quality Control

Our 21-[D(+)-Biotinylamino]-4,7,10,13,16,19-Hexaoxaheneicosanoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and functional testing to ensure optimal performance as a bioconjugation reagent. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with every shipment to guarantee consistency and traceability for your research and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular weight
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Functional Assay	≥ 90% active for biotinylation

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.