Description

5-(Biotinamido)Pentylazide - B4081 is a high-purity, functionalized biotin derivative designed for advanced bioconjugation and labeling applications. This compound is essential for researchers and developers requiring precise, covalent attachment of biotin tags to biomolecules via click chemistry. It is primarily utilized in the pharmaceutical, biotechnology, and diagnostic sectors for applications such as target identification, protein purification, and the development of novel assay platforms.

Application

• Click Chemistry Bioconjugation: Acts as a key reagent for strain-promoted azide-alkyne cycloaddition (SPAAC) to label proteins, antibodies, and other biomolecules with biotin.
• Affinity Probe Development: Used to create biotinylated probes for pull-down assays, target identification, and studying protein-protein interactions.
• Diagnostic Assay Manufacturing: Incorporated into the production of ELISA, lateral flow assays, and other diagnostic kits where stable biotin-streptavidin binding is required.
• Drug Discovery Platforms: Enables the labeling of drug candidates or cellular targets for high-throughput screening and mechanism-of-action studies.
• Cell Surface Engineering: Facilitates the specific labeling of cell surface proteins or glycans for imaging and flow cytometry analysis.
• Material Science Functionalization: Used to biotinylate nanoparticles, polymers, or surfaces for creating advanced biosensors and biomaterials.

Basic Information

Product Name	5-(Biotinamido)Pentylazide - B4081
CAS No.	1349190-76-6
Molecular Formula	C20H35N7O3S
Molecular Weight	453.60 g/mol
Synonyms	Biotin-PEG5-azide; Biotinamidopentyl azide; 5-(Biotinamido)pentyl azide; N-(5-Azidopentyl)biotinamide; Biotin-azide (PEG5 linker); Biotin-Pentyl-Azide; (+)-Biotin-5-azidopentylamide; B4081
EINECS	Contact for details

Quality Control

Every batch of 5-(Biotinamido)Pentylazide - B4081 is manufactured under strict quality management systems and undergoes comprehensive analytical testing to ensure identity, purity, and performance. We provide a detailed Certificate of Analysis (COA) with each shipment, which includes data from HPLC, NMR, and mass spectrometry. Our quality commitment supports applications in GLP and GMP environments, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF; Slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.