Description

2-Bromo-4-Fluoro-5-Methyl-1,3-Dinitrobenzene is a high-purity, multi-functional halogenated nitrobenzene derivative, serving as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it an invaluable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought by R&D chemists and process development teams in the pharmaceutical, agrochemical, and specialty materials industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring halogen and nitro functional groups for further derivatization.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the bromo and fluoro substituents enhance biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: Employed as a reactive handle for bioconjugation and the development of chemical probes due to the reactivity of the nitro and halogen groups.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex azo dyes and pigments, contributing to color fastness and specific spectral properties.
• Cross-Coupling Reactions: A valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form biaryl structures common in many functional molecules.

Basic Information

Item	Details
Product Name	2-Bromo-4-Fluoro-5-Methyl-1,3-Dinitrobenzene
CAS No.	1345471-92-2
Molecular Formula	C7H4BrFN2O4
Molecular Weight	279.02 g/mol
Synonyms	1-Bromo-2-fluoro-5-methyl-3,5-dinitrobenzene; 3-Bromo-4-fluoro-5-methyl-1,2-dinitrobenzene; 2-Bromo-4-fluoro-5-methyl-m-dinitrobenzene; 5-Bromo-3-fluoro-4-methyl-1,2-dinitrobenzene; Benzene, 2-bromo-4-fluoro-5-methyl-1,3-dinitro-; 1345471-92-2
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-Fluoro-5-Methyl-1,3-Dinitrobenzene is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency to meet the rigorous demands of process chemistry and regulatory starting material requirements. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed. A detailed Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, open flames, and incompatible materials such as strong reducing agents and bases. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.