Description

(R)-1-Thiazol-4-Yl-Ethylamine is a chiral amine building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other biologically active molecules, particularly those targeting the central nervous system. Pharmaceutical R&D departments and fine chemical manufacturers need this high-purity chiral synthon to create novel therapeutic candidates with specific stereochemical configurations.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel drug candidates, particularly in neuroscience and antiviral research.
• Asymmetric Synthesis: Used as a chiral auxiliary or resolving agent in stereoselective chemical reactions to produce enantiomerically pure compounds.
• Ligand Precursor: Serves as a precursor for the development of chiral ligands used in catalysis, such as for asymmetric hydrogenation.
• Agrochemical Research: Employed in the discovery and synthesis of new chiral active ingredients for crop protection.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Material Science: A potential monomer or modifier in the synthesis of specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	(R)-1-Thiazol-4-Yl-Ethylamine
CAS No.	1344412-36-7
Molecular Formula	C5H8N2S
Molecular Weight	128.19 g/mol
Synonyms	(R)-1-(Thiazol-4-yl)ethan-1-amine; (R)-1-(4-Thiazolyl)ethylamine; (R)-α-Methyl-4-thiazolemethanamine; (R)-4-(1-Aminoethyl)thiazole; (R)-Thiazol-4-ylethylamine; (R)-TEA; (R)-1-(Thiazol-4-yl)ethylamine hydrochloride (salt form); (R)-1-(4-Thiazolyl)ethanamine
EINECS	Contact for details

Quality Control

Our (R)-1-Thiazol-4-Yl-Ethylamine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain optimal purity and stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.