Description

Trisodium:[(2R,3S,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methoxy-[[[Hydroxy(Oxido)Phosphoryl]Oxy-Oxidophosphoryl]Methyl]Phosphinate is a high-purity nucleotide derivative, specifically a trisodium salt of a modified adenosine triphosphate (ATP) analog. This compound is critical for biochemical research and pharmaceutical development due to its role as a stable, cell-permeable precursor or inhibitor in nucleotide signaling pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in enzymology, molecular biology, and the development of targeted therapeutics for metabolic and proliferative disorders.

Application

• Biochemical Research Reagent: Used as a substrate or inhibitor in enzymatic assays to study kinase, ATPase, and polymerase activity.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel nucleotide-based prodrugs and antiviral/anticancer agents.
• Cell Signaling Studies: Applied in cellular assays to investigate purinergic signaling pathways, energy metabolism, and apoptosis.
• Diagnostic Development: Employed in the formulation of diagnostic kits for monitoring enzymatic functions and metabolic disorders.
• Pre-clinical Drug Discovery: Utilized in high-throughput screening (HTS) platforms to identify and validate new therapeutic targets.
• Life Science Tool Compound: Supplied as a reference standard or tool compound for proteomics and metabolomics research.

Basic Information

Item	Details
Product Name	Trisodium:[(2R,3S,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methoxy-[[[Hydroxy(Oxido)Phosphoryl]Oxy-Oxidophosphoryl]Methyl]Phosphinate
CAS No.	1343364-54-4
Molecular Formula	C11H14N5Na3O14P3
Molecular Weight	629.13 g/mol (anhydrous basis)
Synonyms	Trisodium ATP-γ-S analog; Adenosine 5'-(γ-thiotriphosphate) trisodium salt derivative; P1-(Adenosin-5'-yl) P3-[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl triphosphonate trisodium salt; Modified ATP trisodium salt; Nucleotide triphosphate analog; ATPγS trisodium salt isomer; Purine nucleotide phosphonate
EINECS	Contact for details

Quality Control

Our Trisodium:[(2R,3S,4R,5R)-5-(6-Aminopurin-9-Yl)-3,4-Dihydroxyoxolan-2-Yl]Methoxy-[[[Hydroxy(Oxido)Phosphoryl]Oxy-Oxidophosphoryl]Methyl]Phosphinate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Biological Activity	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.