Description

Biotin-Peg7-Amine CAS NO 1334172-76-7 is a high-purity, heterobifunctional polyethylene glycol (PEG) linker featuring a biotin group for strong streptavidin/avidin binding and a terminal primary amine for conjugation to carboxylates or other reactive groups. This compound is critical for creating stable, site-specific bioconjugates used in advanced diagnostics and targeted drug delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and in vitro diagnostics (IVD) sectors for developing novel therapeutics, biosensors, and assay platforms.

Application

• Conjugation reagent for the synthesis of biotinylated antibodies, proteins, and peptides for immunoassays (ELISA, Western Blot).
• Key intermediate in the development of Antibody-Drug Conjugates (ADCs) and other targeted biotherapeutics.
• Surface functionalization agent for biosensors, microarrays, and solid supports to immobilize biomolecules via amine coupling.
• Tool compound in proteomics and pull-down assays for isolating and studying protein complexes.
• Building block for constructing multifunctional nanoparticles and liposomes for targeted drug delivery.
• Linker for creating fluorescent or enzyme-labeled probes for cellular imaging and flow cytometry.
• Modification of oligonucleotides (e.g., aptamers, primers) for detection and capture applications.

Basic Information

Product Name	Biotin-Peg7-Amine
CAS No.	1334172-76-7
Molecular Formula	C33H62N4O11S
Molecular Weight	722.93 g/mol
Synonyms	Biotin-PEG7-NH2; Biotin-PEG7-amine; 5-((3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-N-(2-(2-(2-(2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethoxy)ethyl)pentanamide; Biotinamido-PEG7-amine; Biotinylated PEG7 amine; Biotin-PEG7-alkylamine; Biotin-Polyethylene glycol-amine (n=7); EZ-Link Biotin-PEG7-Amine
EINECS	Contact for details

Quality Control

Our Biotin-Peg7-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry, to ensure it meets the stringent requirements for research and bioconjugation applications. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to warm to room temperature in a dry environment before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	White to off-white solid or viscous oil
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in DMSO, DMF, water, and common organic solvents

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.